Long acting muscarinic antagonists for the treatment of chronic obstructive pulmonary disease: a review of current and developing drugs
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2017.1276167
Abstract: ABSTRACT Introduction: Long acting muscarinic receptor antagonists (LAMA) reverse airflow obstruction by antagonizing para-sympathetic bronchoconstricting effects within the airways. For years, tiotropium, has been the cornerstone LAMA for chronic obstructive pulmonary disease (COPD) management. Recently,… read more here.
Keywords: chronic obstructive; long acting; obstructive pulmonary; developing drugs ... See more keywords
Developing drugs for the 'undruggable'.
Sign Up to like & getrecommendations! Published in 2020 at "BioTechniques"
DOI: 10.2144/btn-2020-0134
Abstract: There are up to 650,000 'undruggable' protein-protein interactions (PPIs) in the human interactome that can be potentially considered as novel therapeutic targets. How does the 'undruggable' become 'druggable'? read more here.
Keywords: drugs undruggable; developing drugs;