Articles with "developing mnk" as a keyword



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Progress in developing MNK inhibitors.

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Published in 2021 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2021.113420

Abstract: The MNKs (mitogen-activated protein kinase-interacting protein kinases) phosphorylate eIF4E (eukaryotic initiation factor 4 E) at serine 209; eIF4E plays an important role in the translation of cytoplasmic mRNAs, all of which possess a 5' 'cap' structure… read more here.

Keywords: mnk; developing mnk; chemistry; progress developing ... See more keywords