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Published in 2017 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2017.04.011
Abstract: HIGHLIGHTSPrenatal exposure to LCT altered expression of NMDA receptors in developing rats.Alteration in postsynaptic signaling in hippocampus of developing rats also evident.Changes associated with impairment in memory of rats on PD22 and PD45.Changes found to…
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Keywords:
exposure;
developing rats;
lct;
prenatal exposure ... See more keywords
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Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00368
Abstract: Neonatal exposure to isoflurane can result in neuroapoptosis and persistent cognitive impairments. However, the underlying mechanisms remain elusive. Anaphase-promoting complex/cyclosome (APC/C) and its co-activator Cdh1 are E3 ubiquitin ligases that play important roles in the…
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Keywords:
cdh1;
neuronal apoptosis;
isoflurane induced;
developing rats ... See more keywords