Unraveling the Heterogeneous Mutational Signature of Spontaneously Developing Tumors in MLH1−/− Mice
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DOI: 10.3390/cancers11101485
Abstract: Mismatch repair deficient (MMR-D) tumors exemplify the prototypic hypermutator phenotype. Owing to the high mutation rates, plenty of neo-antigens are present on the tumor cells’ surface, ideally shared among different cancer types. The MLH1 knock… read more here.
Keywords: unraveling heterogeneous; developing tumors; spontaneously developing; signature spontaneously ... See more keywords