Report of the use of patient‐derived xenograft models in the development of anticancer drugs in Japan
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DOI: 10.1111/cas.14564
Abstract: Abstract Cell line‐derived xenograft (CDX) models created by implanting cancer cell lines into immunodeficient mice have contributed largely to the development of cancer drug therapies. However, cell lines often lose their original biological characteristics through… read more here.
Keywords: pdx models; development anticancer; derived xenograft; anticancer drugs ... See more keywords
An Overview of the Recent Development of Anticancer Agents Targeting the HIF-1 Transcription Factor
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DOI: 10.3390/cancers13112813
Abstract: Simple Summary As hypoxia-inducible factor 1 (HIF-1) is recognized as a target for cancer therapy, extensive efforts have been devoted to developing its inhibitors. We provide an overview of the latest information about basic, translational,… read more here.
Keywords: development anticancer; factor; hif; overview recent ... See more keywords