The use of the larval development assay for predicting the in vivo efficacy of levamisole against Haemonchus contortus and Trichostrongylus colubriformis.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2018.07.013
Abstract: The larval development assay has been used for many years to measure the sensitivity of the free-living life stages of trichostrongylid nematodes to anthelmintics. The assay has applications in both drug discovery and the diagnosis… read more here.
Keywords: drug; larval development; development assay; efficacy ... See more keywords
Development of an Assay for Soy Isoflavones in Women’s Hair
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14173619
Abstract: Soy isoflavones, at adequate dosages, have estrogenic and anti-thyroidal effects in animals and humans, which can either be beneficial or adverse, depending on the consumer’s physiological status. Hence, this study presents an assay of soy… read more here.
Keywords: soy; hair; soy isoflavones; assay soy ... See more keywords
Development of an LC–MS/MS Assay and Toxicokinetic Characterization of Hexamethylenetetramine in Rats
Sign Up to like & getrecommendations! Published in 2023 at "Toxics"
DOI: 10.3390/toxics11040337
Abstract: Hexamethylenetetramine, an aldehyde-releasing agent, is used as a preservative in various food, cosmetics, and medical treatments, such as a treatment for urinary tract infections. It has been reported to be allergenic on contact with the… read more here.
Keywords: hexamethylenetetramine; assay toxicokinetic; toxicokinetic characterization; development assay ... See more keywords
Inception and development of a LC-MS/MS assay for the multiplexed quantitation of nine human drug transporter biomarkers.
Sign Up to like & getrecommendations! Published in 2024 at "Bioanalysis"
DOI: 10.4155/bio-2023-0197
Abstract: Background: It has become common practice to assess solute carrier transporter (SLC)-mediated drug-drug interactions (DDIs) by quantitating various individual endogenous compounds as biomarkers in human plasma and urine. The goal of this work was to… read more here.
Keywords: development assay; multiplexed quantitation; drug; inception development ... See more keywords