Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Lipids"
DOI: 10.1002/lipd.12331
Abstract: The occurrence of atherosclerosis is closely related to inflammation and lipid metabolism disorder. It has been found that lipopolysaccharide (LPS) could induce inflammation, and tyloxapol (Ty) could induce hyperlipidemia. However, the effects of LPS and… read more here.
Keywords: development atherosclerosis; lipid metabolism; mice; atherosclerosis ... See more keywords
CTRP5 promotes transcytosis and oxidative modification of low-density lipoprotein and the development of atherosclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.09.037
Abstract: BACKGROUND AND AIMS Increased transcytosis of low-density lipoprotein (LDL) across the endothelium and oxidation of LDL deposited within the subendothelial space are crucial early events in atherogenesis. C1q/TNF-related protein (CTRP) 5 is a novel secreted… read more here.
Keywords: development atherosclerosis; ctrp5; density lipoprotein; low density ... See more keywords
GW29-e0161 Effect of Pioglitazone on the Development of Atherosclerosis and its Underlying Mechanisms in Diabetic Apolipoprotein E-Null Mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.027
Abstract: This study aimed to investigate the effects of a PPAR-γ agonist pioglitazone on atherogenesis in a ApoE knockout mice (ApoE-/-) diabetic mice model and cultured vascular smooth muscle cells (VSMCs) model. At the same time,… read more here.
Keywords: effect pioglitazone; development atherosclerosis; pioglitazone development; gw29 e0161 ... See more keywords
Type-2 innate lymphoid cells control the development of atherosclerosis in mice
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15781
Abstract: Type-2 innate lymphoid cells (ILC2) are a prominent source of type II cytokines and are found constitutively at mucosal surfaces and in visceral adipose tissue. Despite their role in limiting obesity, how ILC2s respond to… read more here.
Keywords: type; innate lymphoid; type innate; development atherosclerosis ... See more keywords
Platelets inhibit development of atherosclerosis in atherosclerotic mice.
Sign Up to like & getrecommendations! Published in 2022 at "Cell cycle"
DOI: 10.1080/15384101.2022.2044703
Abstract: Platelets can protect from lipopolysaccharide-induced septic shock by inhibiting inflammation, but it is unknown whether platelets have an anti-atherosclerotic effect. The aim of this study was to investigate the effect of platelet transfusion on atherosclerosis… read more here.
Keywords: inhibit development; platelets inhibit; mice; development atherosclerosis ... See more keywords
Recent Progress of Chronic Stress in the Development of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/4121173
Abstract: With the development of the times, cardiovascular diseases have become the biggest cause of death in the global aging society, causing a serious social burden. Atherosclerosis is a chronic inflammatory disease, which can occur in… read more here.
Keywords: development; development atherosclerosis; disease; chronic stress ... See more keywords
Abstract 218: Pathophysiological Significance of Browning of Perivascular Adipose Tissue in the Development of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.218
Abstract: Background: Perivascular adipose tissue (PVAT) possibly plays a pivotal role in the development of atherosclerosis through its direct local action to the vessels. However, its physiological and molecular mechanisms are less understood. Visceral and subcutaneous… read more here.
Keywords: injury; development atherosclerosis; adipose tissue; tissue ... See more keywords
The Induction of Endothelial Autophagy and Its Role in the Development of Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.831847
Abstract: Increasing attention is now being paid to the important role played by autophagic flux in maintaining normal blood vessel walls. Endothelial cell dysfunction initiates the development of atherosclerosis. In the endothelium, a variety of critical… read more here.
Keywords: role; development atherosclerosis; endothelial cells; induction endothelial ... See more keywords
Diabetes Mellitus Promotes the Development of Atherosclerosis: The Role of NLRP3
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.900254
Abstract: Atherosclerosis is one of the main complications of diabetes mellitus, involving a variety of pathogenic factors. Endothelial dysfunction, inflammation, and oxidative stress are hallmarks of diabetes mellitus and atherosclerosis. Although the ability of diabetes to… read more here.
Keywords: role; development atherosclerosis; mellitus promotes; promotes development ... See more keywords
The Mechanisms of the Development of Atherosclerosis in Prediabetes
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084108
Abstract: Lifestyle changes, such as overeating and underexercising, can increase the risk of prediabetes. Diabetes is one of the leading causes of atherosclerosis, and recently it became clear that the pathophysiology of atherosclerosis progresses even before… read more here.
Keywords: atherosclerosis prediabetes; mechanisms development; atherosclerosis; development atherosclerosis ... See more keywords