Development of broadly neutralizing antibodies targeting the cytomegalovirus subdominant antigen gH.
Sign Up to like & getrecommendations! Published in 2022 at "Communications biology"
DOI: 10.1038/s42003-022-03294-z
Abstract: Human cytomegalovirus (HCMV) is a β-herpesvirus that increases morbidity and mortality in immunocompromised individuals including transplant recipients and newborns. New anti-HCMV therapies are an urgent medical need for diverse patient populations. HCMV infection of a… read more here.
Keywords: broadly neutralizing; targeting cytomegalovirus; development broadly; neutralizing antibodies ... See more keywords
Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers
Sign Up to like & getrecommendations! Published in 2018 at "Retrovirology"
DOI: 10.1186/s12977-018-0443-0
Abstract: Broadly neutralizing antibodies (bNAbs), able to prevent viral entry by diverse global viruses, are a major focus of HIV vaccine design, with data from animal studies confirming their ability to prevent HIV infection. However, traditional… read more here.
Keywords: development broadly; development; neutralizing antibodies; vaccine ... See more keywords