Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300
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DOI: 10.1002/cmdc.202400792
Abstract: The alteration of the lysine acetyltransferase activity and protein–protein interactions of the transcriptional co‐activators CREB‐binding protein (CBP) and p300 is linked to the development of both solid and hematological cancers. To target both functions of… read more here.
Keywords: p300; development c646; cbp p300;