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Published in 2017 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-017-9710-0
Abstract: The discovery of biomarkers able to detect cancer at an early stage, to evaluate its aggressiveness, and to predict the response to therapy remains a major challenge in clinical oncology and precision medicine. In this…
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Keywords:
biomarker discovery;
methods biomarker;
innovative methods;
development cancer ... See more keywords
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Published in 2017 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.05.003
Abstract: Transfer of genetic material from cytoplasmic organelles to the nucleus, an ongoing process, has implications in evolution, aging, and human pathologies such as cancer. The transferred mitochondrial DNA (mtDNA) fragments in the nuclear genome are…
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Keywords:
mechanism development;
numtogenesis mechanism;
development cancer;
biology ... See more keywords
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Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra04590b
Abstract: The possible reasons that caused low response rate and severe side effects of programmed death receptor 1 (PD-1)/programmed death ligand 1 (PD-L1) blockade therapy and corresponding strategies.
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Keywords:
pathway blockade;
immunotherapy based;
development cancer;
cancer immunotherapy ... See more keywords
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Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12867
Abstract: Cancer is one of most the significant threats to human health worldwide, and the primary method of treating solid tumours is surgery. Propofol, one of the most widely used intravenous anaesthetics in surgery, was found…
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Keywords:
surgery;
cancer humans;
propofol development;
development cancer ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13858
Abstract: Histone methylation is one of the most important chromatin posttranslational modifications. It has a range of influences on nuclear functions including epigenetic inheritance, transcriptional regulation and the maintenance of genome integrity. Changes in histone methylation…
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Keywords:
lysine demethylase;
histone;
demethylase;
development cancer ... See more keywords
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Published in 2019 at "Genes"
DOI: 10.3390/genes10100794
Abstract: Development requires the careful orchestration of several biological events in order to create any structure and, eventually, to build an entire organism. On the other hand, the fate transformation of terminally differentiated cells is a…
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Keywords:
factors govern;
development cancer;
cancer;
transcription factors ... See more keywords
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Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19103028
Abstract: The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is constantly deposited, remodelled, and degraded during development until maturity…
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Keywords:
extracellular matrix;
development cancer;
cancer progression;
cancer ... See more keywords
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Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i32.4727
Abstract: BACKGROUND As the malignant tumor, pancreatic cancer with a meager 5-years survival rate has been widely concerning. However, the molecular mechanisms that result in malignant transformation of pancreatic cells remain elusive. AIM To investigate the…
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Keywords:
pancreas development;
pancreatic cancer;
development cancer;
expression ... See more keywords
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Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.12116
Abstract: Nerves have been widely demonstrated to exert major effects in tumor-associated microenvironments. Due to the characteristic innervation of the oral cavity and the fact that cancer-associated pain is a distinct feature of oral squamous cell…
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Keywords:
associated pain;
development cancer;
cancer;
cancer associated ... See more keywords
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Published in 2017 at "Neoplasma"
DOI: 10.4149/neo_2017_301
Abstract: Circular RNAs (circRNAs) are a class of newly-identified non-coding RNA molecules. CircRNAs are conserved across different species and display specific organization, sequence, and expression in disease. Moreover, circRNAs' closed ring structure, insensitivity to RNase, and…
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Keywords:
sponge mir;
development cancer;
expression;
cancer ... See more keywords