Innovative methods for biomarker discovery in the evaluation and development of cancer precision therapies
Sign Up to like & getrecommendations! Published in 2017 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-017-9710-0
Abstract: The discovery of biomarkers able to detect cancer at an early stage, to evaluate its aggressiveness, and to predict the response to therapy remains a major challenge in clinical oncology and precision medicine. In this… read more here.
Keywords: biomarker discovery; methods biomarker; innovative methods; development cancer ... See more keywords
Numtogenesis as a mechanism for development of cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.05.003
Abstract: Transfer of genetic material from cytoplasmic organelles to the nucleus, an ongoing process, has implications in evolution, aging, and human pathologies such as cancer. The transferred mitochondrial DNA (mtDNA) fragments in the nuclear genome are… read more here.
Keywords: mechanism development; numtogenesis mechanism; development cancer; biology ... See more keywords
Development of cancer immunotherapy based on PD-1/PD-L1 pathway blockade
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra04590b
Abstract: The possible reasons that caused low response rate and severe side effects of programmed death receptor 1 (PD-1)/programmed death ligand 1 (PD-L1) blockade therapy and corresponding strategies. read more here.
Keywords: pathway blockade; immunotherapy based; development cancer; cancer immunotherapy ... See more keywords
Effects of propofol on the development of cancer in humans
Sign Up to like & getrecommendations! Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12867
Abstract: Cancer is one of most the significant threats to human health worldwide, and the primary method of treating solid tumours is surgery. Propofol, one of the most widely used intravenous anaesthetics in surgery, was found… read more here.
Keywords: surgery; cancer humans; propofol development; development cancer ... See more keywords
Histone demethylase lysine demethylase 5B in development and cancer
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13858
Abstract: Histone methylation is one of the most important chromatin posttranslational modifications. It has a range of influences on nuclear functions including epigenetic inheritance, transcriptional regulation and the maintenance of genome integrity. Changes in histone methylation… read more here.
Keywords: lysine demethylase; histone; demethylase; development cancer ... See more keywords
Transcription Factors That Govern Development and Disease: An Achilles Heel in Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10100794
Abstract: Development requires the careful orchestration of several biological events in order to create any structure and, eventually, to build an entire organism. On the other hand, the fate transformation of terminally differentiated cells is a… read more here.
Keywords: factors govern; development cancer; cancer; transcription factors ... See more keywords
Role of Extracellular Matrix in Development and Cancer Progression
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19103028
Abstract: The immense diversity of extracellular matrix (ECM) proteins confers distinct biochemical and biophysical properties that influence cell phenotype. The ECM is highly dynamic as it is constantly deposited, remodelled, and degraded during development until maturity… read more here.
Keywords: extracellular matrix; development cancer; cancer progression; cancer ... See more keywords
Integrative analysis of the inverse expression patterns in pancreas development and cancer progression
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v25.i32.4727
Abstract: BACKGROUND As the malignant tumor, pancreatic cancer with a meager 5-years survival rate has been widely concerning. However, the molecular mechanisms that result in malignant transformation of pancreatic cells remain elusive. AIM To investigate the… read more here.
Keywords: pancreas development; pancreatic cancer; development cancer; expression ... See more keywords
Calcitonin gene-related peptide: A promising bridge between cancer development and cancer-associated pain in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.12116
Abstract: Nerves have been widely demonstrated to exert major effects in tumor-associated microenvironments. Due to the characteristic innervation of the oral cavity and the fact that cancer-associated pain is a distinct feature of oral squamous cell… read more here.
Keywords: associated pain; development cancer; cancer; cancer associated ... See more keywords
Detection and characterization of ciRS-7: a potential promoter of the development of cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Neoplasma"
DOI: 10.4149/neo_2017_301
Abstract: Circular RNAs (circRNAs) are a class of newly-identified non-coding RNA molecules. CircRNAs are conserved across different species and display specific organization, sequence, and expression in disease. Moreover, circRNAs' closed ring structure, insensitivity to RNase, and… read more here.
Keywords: sponge mir; development cancer; expression; cancer ... See more keywords