miR-337-5p promotes the development of cardiac hypertrophy by targeting Ubiquilin-1 (UBQLN1).
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1964892
Abstract: Cardiac hypertrophy is an adaptive response of the myocardium to the pressure overload of the heart. MicroRNAs (miRNAs/miRs) are shown to be directly involved in the development of cardiac hypertrophy. However, the function of miR-337-5p… read more here.
Keywords: mir 337; cardiac hypertrophy; development cardiac; hypertrophy targeting ... See more keywords
Ryanodine Receptor Type 2 Plays a Role in the Development of Cardiac Fibrosis under Mechanical Stretch Through TGFβ-1.
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DOI: 10.1536/ihj.16-572
Abstract: Ryanodine receptor type 2 (RyR-2), the main Ca2+ release channel from sarcoplasmic reticulum in cardiomyocytes, plays a vital role in the regulation ofmyocardial contractile function and cardiac hypertrophy. However, the role of RyR-2 in cardiac… read more here.
Keywords: development cardiac; fibrosis; cardiac fibrosis; ryr ... See more keywords
Role of Klotho and AGE/RAGE-Wnt/β-Catenin Signalling Pathway on the Development of Cardiac and Renal Fibrosis in Diabetes
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DOI: 10.3390/ijms24065241
Abstract: Fibrosis plays an important role in the pathogenesis of long-term diabetic complications and contributes to the development of cardiac and renal dysfunction. The aim of this experimental study, performed in a long-term rat model, which… read more here.
Keywords: role; wnt catenin; development cardiac; rage ... See more keywords
Endothelial TGF-β signaling instructs smooth muscle cell development in the cardiac outflow tract
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DOI: 10.7554/elife.57603
Abstract: The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects in OFT development can lead… read more here.
Keywords: tgf signaling; tgf; development cardiac; outflow tract ... See more keywords