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   Articles with "development cell" as a keyword



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The development of cell senescence

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recommendations! Published in 2019 at "Experimental Gerontology"

DOI: 10.1016/j.exger.2019.110742

Abstract: Cellular senescence was traditionally considered a stress response that protected the organism by limiting the proliferation of damaged and unwanted cells. However, the recent identification of developmentally-programmed cellular senescence during embryo development has changed our… read more here.

Keywords: development cell; cell senescence; senescence; developmental senescence ... See more keywords

Ethical issues and public communication in the development of cell-based treatments for COVID-19: Lessons from the pandemic

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recommendations! Published in 2021 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2021.09.005

Abstract: The significant morbidity and mortality of coronavirus disease 19 (COVID-19) prompted a global race to develop new therapies. These include interventions using cell- or cell-derived products, several of which are being tested in well-designed, properly… read more here.

Keywords: cell based; cell; development cell; public communication ... See more keywords

Development of a Cell-Based Assay for Measuring Base Excision Repair Responses

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-12963-7

Abstract: Base excision repair (BER) is the predominant pathway for coping with most forms of hydrolytic, oxidative or alkylative DNA damage. Measuring BER capacity in living cells is valuable for both basic science applications and epidemiological… read more here.

Keywords: development cell; base excision; excision repair; cell based ... See more keywords

Compliance in Non-Clinical Development of Cell-, Gene-, and Tissue-Based Medicines: Good Practice for Better Therapies

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recommendations! Published in 2022 at "Stem Cells Translational Medicine"

DOI: 10.1093/stcltm/szac046

Abstract: Abstract The development of cell-, gene- and tissue engineering (CGT)-based therapies must adhere to strict pharmaceutical quality management standards, as for any other biological or small-molecule drug. However, early developments often failed to fully comply… read more here.

Keywords: compliance non; development; development cell; cell gene ... See more keywords

Development of B Cell Memory in Malaria

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recommendations! Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.00559

Abstract: A single exposure to many viral and bacterial pathogens typically induces life-long immunity, however, the development of the protective immunity to Plasmodium parasites is strikingly less efficient and achieves only partial protection, with adults residing… read more here.

Keywords: malaria; development cell; cell memory; cell ... See more keywords

Novel scFv against Notch Ligand JAG1 Suitable for Development of Cell Therapies toward JAG1-Positive Tumors

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recommendations! Published in 2023 at "Biomolecules"

DOI: 10.3390/biom13030459

Abstract: The Notch signaling ligand JAG1 is overexpressed in various aggressive tumors and is associated with poor clinical prognosis. Hence, therapies targeting oncogenic JAG1 hold great potential for the treatment of certain tumors. Here, we report… read more here.

Keywords: anti jag1; ligand jag1; jag1; jag1 positive ... See more keywords
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The Role of m6A Modifications in B-Cell Development and B-Cell-Related Diseases

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24054721

Abstract: B cells are a class of professional antigen-presenting cells that produce antibodies to mediate humoral immune response and participate in immune regulation. m6A modification is the most common RNA modification in mRNA; it involves almost… read more here.

Keywords: cell; cell related; development cell; cell development ... See more keywords

T Cell Immunity To Enterovirus 71 Infection In Humans And Implications For Vaccine Development

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recommendations! Published in 2018 at "International Journal of Medical Sciences"

DOI: 10.7150/ijms.26450

Abstract: Enterovirus 71 (EV-A71) is one of the major pathogens causing hand, foot and mouth disease (HFMD). Some strains can lead to neurological disease and fatality in children. Up to date, there is no FDA-approved vaccine… read more here.

Keywords: development cell; enterovirus; cell immunity; cell ... See more keywords