TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation
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DOI: 10.1016/j.molmet.2018.01.003
Abstract: Objective Diabetic retinopathy (DR) is induced by an accumulation of reactive metabolites such as ROS, RNS, and RCS species, which were reported to modulate the activity of cation channels of the TRPC family. In this… read more here.
Keywords: retinopathy; diabetic retinopathy; development diabetic; activity ... See more keywords
Toll‐like receptor inflammatory cascade and the development of diabetic kidney disease in children and adolescents with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.15884
Abstract: This study aimed to evaluate the association of toll‐like receptor (TLR) inflammatory cascade with the development of diabetic kidney disease (DKD) in children and adolescents with type 1 diabetes (T1D). read more here.
Keywords: toll like; cascade development; like receptor; inflammatory cascade ... See more keywords
Depletion of Gprc5a Promotes Development of Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2017101135
Abstract: Background Renal glomeruli are the primary target of injury in diabetic nephropathy (DN), and the glomerular podocyte has a key role in disease progression.Methods To identify potential novel therapeutic targets for DN, we performed high-throughput… read more here.
Keywords: gprc5a; promotes development; depletion gprc5a; diabetic nephropathy ... See more keywords
LncRNA NEAT1 accelerates the occurrence and development of diabetic nephropathy by sponging miR-23c.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202002_20190
Abstract: OBJECTIVE LncRNA nuclear enriched abundant transcript 1 (NEAT1) has been reported to play an oncogenic role in the occurrence and development of diabetic nephropathy (DN). The aim of our study was to investigate the potential… read more here.
Keywords: sponging mir; mir 23c; lncrna neat1; diabetic nephropathy ... See more keywords