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   Articles with "development disease" as a keyword



Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers

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recommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.70029

Abstract: Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction… read more here.

Keywords: disease model; delirium; development disease; postoperative delirium ... See more keywords
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Effects of Prenatal Nutrition and the Role of the Placenta in Health and Disease.

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recommendations! Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7614-0_2

Abstract: Epidemiologic studies identified the linkage between exposures to stresses, including the type and plane of nutrition in utero with development of disease in later life. Given the critical roles of the placenta in mediating transport… read more here.

Keywords: effects prenatal; development disease; disease; role placenta ... See more keywords

The multisystemic functions of FOXD1 in development and disease

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recommendations! Published in 2018 at "Journal of Molecular Medicine"

DOI: 10.1007/s00109-018-1665-2

Abstract: Transcription factors (TFs) participate in a wide range of cellular processes due to their inherent function as essential regulatory proteins. Their dysfunction has been linked to numerous human diseases. The forkhead box (FOX) family of… read more here.

Keywords: development disease; multisystemic functions; disease; foxd1 development ... See more keywords

Purinergic signaling in the retina: From development to disease

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recommendations! Published in 2019 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2018.10.016

Abstract: Retinal injuries and diseases are major causes of human disability involving vision impairment by the progressive and permanent loss of retinal neurons. During development, assembly of this tissue entails a successive and overlapping, signal-regulated engagement… read more here.

Keywords: signaling retina; development disease; retina development; development ... See more keywords
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Boundary cap cells in development and disease

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recommendations! Published in 2017 at "Current Opinion in Neurobiology"

DOI: 10.1016/j.conb.2017.11.003

Abstract: Broad plasticity of the peripheral glia is an emerging concept during development of the peripheral nervous system (PNS). Recent studies have identified the neural crest-derived boundary caps (BCs), as a multitask stem cell population of… read more here.

Keywords: development disease; cells development; cap cells; disease ... See more keywords

Role of miRNAs in development and disease: Lessons learnt from small organisms

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recommendations! Published in 2017 at "Life Sciences"

DOI: 10.1016/j.lfs.2017.07.017

Abstract: &NA; MicroRNAs (miRNAs) constitute a class of small (18–22 nucleotides) non‐coding RNAs that regulate gene expression at the post‐transcriptional level. Caenorhabditis elegans, Drosophila melanogaster, and many other small organisms have been instrumental in deciphering the… read more here.

Keywords: development disease; small organisms; functions mirnas; role ... See more keywords

Rigidity transitions in development and disease.

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recommendations! Published in 2022 at "Trends in cell biology"

DOI: 10.1016/j.tcb.2021.12.006

Abstract: Although rigidity and jamming transitions have been widely studied in physics and material science, their importance in a number of biological processes, including embryo development, tissue homeostasis, wound healing, and disease progression, has only begun… read more here.

Keywords: transitions development; rigidity; rigidity transitions; development disease ... See more keywords
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The ciliary protein Rpgrip1l in development and disease.

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recommendations! Published in 2018 at "Developmental biology"

DOI: 10.1016/j.ydbio.2018.07.024

Abstract: RPGRIP1L is an evolutionary highly conserved gene encoding a protein that localises at the transition zone of primary cilia. Mutations in RPGRIP1L result in ciliopathies, severe human diseases caused by dysfunctional cilia. Patients with mutations… read more here.

Keywords: rpgrip1l development; development disease; protein rpgrip1l; ciliary protein ... See more keywords

Zebrafish embryogenesis - A framework to study regulatory RNA elements in development and disease.

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recommendations! Published in 2019 at "Developmental biology"

DOI: 10.1016/j.ydbio.2019.01.008

Abstract: Post-transcriptional gene regulation through the recognition of specific elements in mRNAs is an important determinant of gene expression. The cis elements are recognised by RNA binding proteins (RBPs) and/or small non-coding RNAs, which then orchestrate… read more here.

Keywords: development disease; rna elements; zebrafish embryogenesis; study ... See more keywords

Ubiquitylation at the crossroads of development and disease

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recommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"

DOI: 10.1038/nrm.2017.83

Abstract: Human development requires intricate cell specification and communication pathways that allow an embryo to generate and appropriately connect more than 200 different cell types. Key to the successful completion of this differentiation programme is the… read more here.

Keywords: development disease; ubiquitylation crossroads; ubiquitylation; crossroads development ... See more keywords

Vascular Organization: Lessons from Development and Disease.

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recommendations! Published in 2024 at "Cold Spring Harbor perspectives in medicine"

DOI: 10.1101/cshperspect.a041160

Abstract: Organ formation requires tight coordination with vascular growth. Intricate networks of blood vessels course through all organs and tissues and are composed of both endothelial cells (ECs) and associated mural cells. Despite decades of research… read more here.

Keywords: development disease; lessons development; organization lessons; development ... See more keywords