Effects of Prenatal Nutrition and the Role of the Placenta in Health and Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7614-0_2
Abstract: Epidemiologic studies identified the linkage between exposures to stresses, including the type and plane of nutrition in utero with development of disease in later life. Given the critical roles of the placenta in mediating transport… read more here.
Keywords: effects prenatal; development disease; disease; role placenta ... See more keywords
The multisystemic functions of FOXD1 in development and disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-018-1665-2
Abstract: Transcription factors (TFs) participate in a wide range of cellular processes due to their inherent function as essential regulatory proteins. Their dysfunction has been linked to numerous human diseases. The forkhead box (FOX) family of… read more here.
Keywords: development disease; multisystemic functions; disease; foxd1 development ... See more keywords
Purinergic signaling in the retina: From development to disease
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2018.10.016
Abstract: Retinal injuries and diseases are major causes of human disability involving vision impairment by the progressive and permanent loss of retinal neurons. During development, assembly of this tissue entails a successive and overlapping, signal-regulated engagement… read more here.
Keywords: signaling retina; development disease; retina development; development ... See more keywords
Boundary cap cells in development and disease
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.11.003
Abstract: Broad plasticity of the peripheral glia is an emerging concept during development of the peripheral nervous system (PNS). Recent studies have identified the neural crest-derived boundary caps (BCs), as a multitask stem cell population of… read more here.
Keywords: development disease; cells development; cap cells; disease ... See more keywords
Role of miRNAs in development and disease: Lessons learnt from small organisms
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.07.017
Abstract: &NA; MicroRNAs (miRNAs) constitute a class of small (18–22 nucleotides) non‐coding RNAs that regulate gene expression at the post‐transcriptional level. Caenorhabditis elegans, Drosophila melanogaster, and many other small organisms have been instrumental in deciphering the… read more here.
Keywords: development disease; small organisms; functions mirnas; role ... See more keywords
Rigidity transitions in development and disease.
Sign Up to like & getrecommendations! Published in 2022 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2021.12.006
Abstract: Although rigidity and jamming transitions have been widely studied in physics and material science, their importance in a number of biological processes, including embryo development, tissue homeostasis, wound healing, and disease progression, has only begun… read more here.
Keywords: transitions development; rigidity; rigidity transitions; development disease ... See more keywords
The ciliary protein Rpgrip1l in development and disease.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.07.024
Abstract: RPGRIP1L is an evolutionary highly conserved gene encoding a protein that localises at the transition zone of primary cilia. Mutations in RPGRIP1L result in ciliopathies, severe human diseases caused by dysfunctional cilia. Patients with mutations… read more here.
Keywords: rpgrip1l development; development disease; protein rpgrip1l; ciliary protein ... See more keywords
Zebrafish embryogenesis - A framework to study regulatory RNA elements in development and disease.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.01.008
Abstract: Post-transcriptional gene regulation through the recognition of specific elements in mRNAs is an important determinant of gene expression. The cis elements are recognised by RNA binding proteins (RBPs) and/or small non-coding RNAs, which then orchestrate… read more here.
Keywords: development disease; rna elements; zebrafish embryogenesis; study ... See more keywords
Ubiquitylation at the crossroads of development and disease
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/nrm.2017.83
Abstract: Human development requires intricate cell specification and communication pathways that allow an embryo to generate and appropriately connect more than 200 different cell types. Key to the successful completion of this differentiation programme is the… read more here.
Keywords: development disease; ubiquitylation crossroads; ubiquitylation; crossroads development ... See more keywords
In Vitro Models to Study Human Lung Development, Disease and Homeostasis.
Sign Up to like & getrecommendations! Published in 2017 at "Physiology"
DOI: 10.1152/physiol.00041.2016
Abstract: The main function of the lung is to support gas exchange, and defects in lung development or diseases affecting the structure and function of the lung can have fatal consequences. Most of what we currently… read more here.
Keywords: development disease; lung development; human lung; lung ... See more keywords
MicroRNAs in kidney development and disease
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.158277
Abstract: MicroRNAs (miRNAs) belong to a class of endogenous small noncoding RNAs that regulate gene expression at the posttranscriptional level, through both translational repression and mRNA destabilization. They are key regulators of kidney morphogenesis, modulating diverse… read more here.
Keywords: kidney; development disease; micrornas kidney; kidney development ... See more keywords