Development of fluorogenic substrates for colorectal tumor-related neuropeptidases for activity-based diagnosis
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DOI: 10.1039/d2sc07029d
Abstract: The M3 metalloproteases, neurolysin and THOP1, are neuropeptidases that are expressed in various tissues and metabolize neuropeptides, such as neurotensin. The biological roles of these enzymes are not well characterized, partially because the chemical tools… read more here.
Keywords: fluorogenic substrates; diagnosis; development fluorogenic; activity ... See more keywords