Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome
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DOI: 10.1038/s41598-018-28314-z
Abstract: Wolfram syndrome (WS) is a rare autosomal recessive disorder caused by mutations in the WFS1 (Wolframin1) gene. The syndrome first manifests as diabetes mellitus, followed by optic nerve atrophy, deafness, and neurodegeneration. The underlying mechanism… read more here.
Keywords: glucose intolerance; treatment; wolfram syndrome; development glucose ... See more keywords