Development of Human Recombinant Leptospirosis Vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1884-4_16
Abstract: Leptospirosis is a bacterial zoonotic disease with significant impact on health all over the world. Currently, bacterins are the only vaccines available for prevention of this disease, despite several drawbacks. In an effort to develop… read more here.
Keywords: development; development human; leptospirosis; leptospirosis vaccines ... See more keywords
Towards the development of human immune-system-on-a-chip platforms
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2018.10.003
Abstract: Organ-on-a-chip (OoCs) platforms could revolutionize drug discovery and might ultimately become essential tools for precision therapy. Although many single-organ and interconnected systems have been described, the immune system has been comparatively neglected, despite its pervasive… read more here.
Keywords: system; towards development; immune system; human immune ... See more keywords
Development of Human Carbonic Anhydrase II Heterobifunctional Degraders
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c01843
Abstract: Human carbonic anhydrase II (hCAII) is a metalloenzyme essential to critical physiological processes in the body. hCA inhibitors are used clinically for the treatment of indications ranging from glaucoma to epilepsy. Targeted protein degraders have… read more here.
Keywords: human carbonic; development human; carbonic anhydrase; heterobifunctional degraders ... See more keywords
In Vitro Development of Human iPSC-Derived Functional Neuronal Networks on Laser-Fabricated 3D Scaffolds.
Sign Up to like & getrecommendations! Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c16616
Abstract: Neural progenitor cells generated from human induced pluripotent stem cells (hiPSCs) are the forefront of ″brain-on-chip″ investigations. Viable and functional hiPSC-derived neuronal networks are shaping powerful in vitro models for evaluating the normal and abnormal… read more here.
Keywords: neuronal networks; vitro development; human ipsc; ipsc derived ... See more keywords
The Development of Human Papillomavirus (HPV) Vaccines and Current Barriers to Implementation
Sign Up to like & getrecommendations! Published in 2021 at "Immunological Investigations"
DOI: 10.1080/08820139.2021.1897612
Abstract: ABSTRACT The identification of the human papillomavirus (HPV) as the causative agent of multiple cancers allowed for the development of vaccines and immunization strategies to prevent cancers caused by HPV infection. The public health ramifications… read more here.
Keywords: papillomavirus hpv; hpv; development human; human papillomavirus ... See more keywords
Youth mobility and the development of human capital: is there a Southern European model?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ethnic and Migration Studies"
DOI: 10.1080/1369183x.2019.1679417
Abstract: ABSTRACT Recent Southern European migration is characterised by important flows of higher-skilled young persons. The balance between the risk of a new brain drain and brain waste and the opportunity of brain gain depends on… read more here.
Keywords: capital; southern european; youth mobility; human capital ... See more keywords
Early development of the human dentition revisited
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anatomy"
DOI: 10.1111/joa.12825
Abstract: In this review, classical data on the early steps in human odontogenesis are summarized and updated with specific insights into the development of the upper and lower embryonic jaws to help in understanding some oral… read more here.
Keywords: early development; upper lower; dentition; human dentition ... See more keywords
Flavor Perception and Preference Development in Human Infants
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Nutrition and Metabolism"
DOI: 10.1159/000478759
Abstract: As most parents and caregivers are aware, feeding children a nutritionally balanced diet can be challenging. Children are born with a biological predisposition to prefer sweet and to avoid bitter foods such as green leafy… read more here.
Keywords: preference development; healthful foods; flavor perception; perception preference ... See more keywords
New Insights Into the Development of Human Tool Use
Sign Up to like & getrecommendations! Published in 2017 at "Current Directions in Psychological Science"
DOI: 10.1177/0963721417692035
Abstract: If tool use requires higher level cognitive abilities, how is it that many animals show the capacity to use tools? New research on the development of human tool use offers a way to resolve this… read more here.
Keywords: research; use; tool use; human tool ... See more keywords
Development of the Human Arterial Valves: Understanding Bicuspid Aortic Valve
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.802930
Abstract: Abnormalities in the arterial valves are some of the commonest congenital malformations, with bicuspid aortic valve (BAV) occurring in as many as 2% of the population. Despite this, most of what we understand about the… read more here.
Keywords: aortic valve; bicuspid aortic; arterial valves; development human ... See more keywords
Development of Human Monoclonal Antibody for Claudin-3 Overexpressing Carcinoma Targeting
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom10010051
Abstract: Most malignant tumors originate from epithelial tissues in which tight junctions mediate cell–cell interactions. Tight junction proteins, especially claudin-3 (CLDN3), are overexpressed in various cancers. Claudin-3 is exposed externally during tumorigenesis making it a potential… read more here.
Keywords: development human; cldn3; carcinoma; monoclonal antibody ... See more keywords