Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1
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DOI: 10.1002/cmdc.202400284
Abstract: A conserved intracellular allosteric binding site (IABS) was recently identified at several G protein‐coupled receptors (GPCRs). This target site allows the binding of allosteric modulators and enables a new mode of GPCR inhibition. Herein, we… read more here.
Keywords: development nanobret; detect intracellular; ccr6 cxcr1; assay platform ... See more keywords