Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-88809-0
Abstract: The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications. Of greatest interest is the ~ 300 amino… read more here.
Keywords: development neutralizing; neutralizing diagnostic; monoclonal antibodies; sars cov ... See more keywords
CTLA4‐Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats
Sign Up to like & getrecommendations! Published in 2022 at "Haemophilia"
DOI: 10.1111/hae.14573
Abstract: Immunogenicity causing development of anti‐drug antibodies (ADAs) are major challenges in the treatment of haemophilia, as well as other diseases where proteins are used for treatment. Furthermore, it is a complication for preclinical testing of… read more here.
Keywords: ctla4 prevents; development; neutralizing antibody; treatment ... See more keywords