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Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.113973
Abstract: The epidemic of obesity has become pandemic, putting a significant burden on the world's healthcare system. While the heritability of the disease is high, all the identified genetic variants associated to obesity account for a…
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Keywords:
development obesity;
epigenetics development;
pharmacology;
obesity ... See more keywords
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Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126474
Abstract: Excessive energy intake, poor physical exercise and genetics/epigenetics are instrumental for the development of obesity. Because of rapidly emerging evidences related to off-target effects and toxicity of anti-obesity drugs, there is a need to search…
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Keywords:
development obesity;
dietary saponins;
nutritional effects;
effects dietary ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41713-0
Abstract: Obesity is a debilitating disease that has become a global epidemic. Although progress is being made, the underlying molecular mechanism by which obesity develops still remains elusive. Recently, we reported that the expression levels of…
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Keywords:
development obesity;
brd7;
deficiency leads;
brd7 deficiency ... See more keywords
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Published in 2022 at "Thorax"
DOI: 10.1136/thoraxjnl-2021-217867
Abstract: Introduction Obesity is a known risk factor for asthma. Although some evidence showed asthma causing obesity in children, the link between asthma and obesity has not been investigated in adults. Methods We used data from…
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Keywords:
ecrhs;
cohort study;
obesity;
ecrhs ecrhs ... See more keywords
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Published in 2018 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s161808
Abstract: Introduction The small peptide transporter 1 (PepT-1) and adipose phospholipase A2 (AdPLA) play a key role in the development of obesity. However, there are no data assessing the impact of PepT-1 (SLC15A1) and AdPLA (PLA2G16)…
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Keywords:
development obesity;
pla2g16 genes;
slc15a1 pla2g16;
chinese subjects ... See more keywords
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2
Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19074124
Abstract: Background: The alarming increase in childhood obesity is a global public health problem since it has significant health consequences. This cross-sectional study aimed to identify the potentially modifiable risk factors for developing excess weight and…
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Keywords:
excess weight;
habits development;
influence lifestyle;
lifestyle habits ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22042163
Abstract: Obesity is rapidly dispersing all around the world and is closely associated with a high risk of metabolic diseases such as insulin resistance, dyslipidemia, and nonalcoholic fatty liver disease (NAFLD), leading to carcinogenesis, especially hepatocellular…
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Keywords:
cancer;
obesity;
development obesity;
adipose tissue ... See more keywords