Articles with "development orally" as a keyword



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Development of orally bioavailable prodrugs of fulvestrant for the treatment of metastatic/advanced breast cancer.

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.15_suppl.e13027

Abstract: e13027 Background: Fulvestrant, a potent, selective estrogen receptor degrader, is a primary drug of choice for treating advanced metastatic hormone receptor-positive breast cancer in postmenopausal women following anti-estrogen therapy. However, the existing therapy limits to… read more here.

Keywords: bioavailability; breast cancer; prodrugs fulvestrant; development orally ... See more keywords
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Erratum: Discovery and Preclinical Development of Orally Active Small Molecules That Exhibit Highly Selective Follicle Stimulating Hormone Receptor Agonism

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Published in 2021 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.672778

Abstract: [This corrects the article DOI: 10.3389/fphar.2020.602593.]. read more here.

Keywords: development orally; preclinical development; orally active; active small ... See more keywords