Synthesis of Noraugustamine and Development of an Oxidative Heck/Aza-Wacker Cascade Cyclization.
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DOI: 10.1021/acs.orglett.2c00948
Abstract: Radical and transition metal-catalyzed cascade cyclization strategies were investigated with respect to the synthesis of the tetracyclic core of the augustamine-type Amaryllidaceae alkaloids. These studies resulted in the synthesis of noraugustamine and the development of… read more here.
Keywords: development oxidative; cascade cyclization; oxidative heck; noraugustamine development ... See more keywords