The development of peptide- and oligonucleotide-based drugs to prevent the formation of abnormal tau in tauopathies
Sign Up to like & getrecommendations! Published in 2023 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2200245
Abstract: ABSTRACT Introduction Tauopathies represent clinicopathological entities with increased and abnormal glial and/or neuronal inclusions of tau, a microtubule-binding protein. Antisense oligonucleotides (ASOs) are a promising therapeutic approach for treating tauopathies as they can target tau… read more here.
Keywords: tau; peptide oligonucleotide; expression; development peptide ... See more keywords
Development of Peptide Biopharmaceuticals in Russia
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DOI: 10.3390/pharmaceutics14040716
Abstract: Peptides are low-molecular-weight substances that participate in numerous important physiological functions, such as human growth and development, stress, regulation of the emotional state, sexual behavior, and immune responses. Their mechanisms of action are based on… read more here.
Keywords: peptide biopharmaceuticals; development; peptide; development peptide ... See more keywords