Development of a population pharmacokinetic (PPK) model of intravenous (IV) trastuzumab in patients with a variety of solid tumors to support dosing and treatment recommendations.
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DOI: 10.1200/jco.2017.35.15_suppl.2525
Abstract: 2525Background: The aim of this analysis was to develop a PPK model for IV trastuzumab (Herceptin), to assess the impact of patient covariates on PK, and perform simulations to support dosing recommendations. Methods: Serum trastuzumab… read more here.
Keywords: development population; support dosing; ppk model; trastuzumab ... See more keywords