Sensory nerves impede the formation of tertiary lymphoid structures and development of protective anti-melanoma immune responses.
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DOI: 10.1158/2326-6066.cir-22-0110
Abstract: Peripheral neurons comprise a critical component of the tumor microenvironment (TME). The role of the autonomic innervation in cancer has been firmly established. However, the effect of the afferent (sensory) neurons on tumor progression remains… read more here.
Keywords: sensory nerves; melanoma; immune responses; development protective ... See more keywords