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Published in 2020 at "Medicinal research reviews"
DOI: 10.1002/med.21676
Abstract: Glioblastoma is the most aggressive primary brain tumor in adults. The prognosis of patients with primary glioblastoma treated with the current standard of care, tumor resection followed by radiation therapy and auxiliary temozolomide, remains poor.…
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Keywords:
drug development;
development targeted;
advances drug;
drug ... See more keywords
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Published in 2022 at "European Journal of Medicinal Chemistry"
DOI: 10.1016/j.ejmech.2022.114121
Abstract: Recently, a novel coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised global concerns, being the etiological agent of the current pandemic infectious coronavirus disease 2019 (COVID-19). Specific prophylactic treatments like vaccines,…
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Keywords:
development;
sars cov;
inhibition;
tnp ... See more keywords
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Published in 2022 at "Modern rheumatology"
DOI: 10.1093/mr/roac096
Abstract: IgG4-related disease (IgG4-RD) is a systemic disease characterized by high serum IgG4 levels, infiltration of lymphocytes and IgG4-positive plasma cells into affected tissues, and subsequent fibrosis, forming mass, nodular, and thickened lesions in organs. Although…
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Keywords:
igg4 related;
targeted therapies;
disease;
development targeted ... See more keywords
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Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001208
Abstract: Purpose of review The purpose of this review is to describe key pharmacologic considerations to inform strategies in drug development for pediatric cancer. Recent findings Main themes that will be discussed include considering patient specific…
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Keywords:
development;
development targeted;
importance pharmacologic;
targeted anticancer ... See more keywords
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Published in 2017 at "AIDS Research and Therapy"
DOI: 10.1186/s12981-017-0165-8
Abstract: Finding new adjuvants is an integrated component of the efforts in developing an effective HIV-1 vaccine. Compared with traditional adjuvants, a modern adjuvant in the context of HIV-1 prevention would elicit a durable and potent…
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Keywords:
hiv vaccines;
targeted adjuvants;
adjuvants hiv;
development targeted ... See more keywords
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Published in 2023 at "Studies in health technology and informatics"
DOI: 10.3233/shti230102
Abstract: Alerting systems have a strong potential to improve quality of care in hospital by ensuring that clinicians provide more effective and timely care to their patients. Many systems have been implemented but often fail to…
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Keywords:
system;
conception development;
development targeted;
alert system ... See more keywords