Chemical Development of Therapeutic Oligonucleotides.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9670-4_1
Abstract: The development of several different chemical modifications of nucleic acids, with improved base-pairing affinity and specificity as well as increased resistance against nucleases, has been described. These new chemistries have allowed the synthesis of different… read more here.
Keywords: development therapeutic; chemical development; biology; development ... See more keywords
Antimicrobial peptides – Advances in development of therapeutic applications
Sign Up to like & getrecommendations! Published in 2020 at "Life Sciences"
DOI: 10.1016/j.lfs.2020.118407
Abstract: The severe infection is becoming a significant health problem which threaten the lives of patients and the safety and economy of society. In the way of finding new strategy, antimicrobial peptides (AMPs) - an important… read more here.
Keywords: peptides advances; development therapeutic; therapeutic applications; advances development ... See more keywords
Development and Therapeutic Implications of Tyrosine Kinase 2 Inhibitors.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01800
Abstract: Janus kinases (JAKs) are central components in cytokine signaling pathways. A number of small molecule JAK inhibitors have been approved to treat a wide range of inflammatory and autoimmune diseases. Due to safety concerns of… read more here.
Keywords: kinase; tyk2 inhibitors; tyrosine kinase; therapeutic implications ... See more keywords
Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases
Sign Up to like & getrecommendations! Published in 2020 at "ACS Central Science"
DOI: 10.1021/acscentsci.0c00272
Abstract: Since the outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2 virus, this disease has spread rapidly around the globe. Considering the potential threat of a pandemic, scien... read more here.
Keywords: research development; development therapeutic; vaccines covid; coronavirus ... See more keywords
P06.12.B Microbiota-gut-brain axis in glioblastoma development and therapeutic resistance
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae144.149
Abstract: Glioblastoma (GB) is the most common subtype of glioma in adults. Despite treatment through tumor resection associated with chemo and radiotherapies, this cancer still has a very poor prognosis. Factors contributing to etiology, pathogenesis, or… read more here.
Keywords: development therapeutic; therapeutic resistance; gut; microbiota ... See more keywords
Development of the Therapeutic Alliance in Alternative Settings to Psychiatric Hospitalization: An Open Comparative Study.
Sign Up to like & getrecommendations! Published in 2024 at "Psychiatric services"
DOI: 10.1176/appi.ps.20230009
Abstract: Patient-therapist alliance in two alternative treatment settings developed similarly to that in traditional psychiatric hospitalization. read more here.
Keywords: alliance; psychiatric hospitalization; therapeutic alliance; development therapeutic ... See more keywords
NF-κB pathway and angiogenesis: insights into colorectal cancer development and therapeutic targets
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Medical Research"
DOI: 10.1186/s40001-024-02168-w
Abstract: Colorectal cancer (CRC) is currently ranked as the third most common type of cancer, contributing significantly to mortality and morbidity worldwide. Epigenetic and genetic changes occurred during CRC progression resulted in the cell proliferation, cancer… read more here.
Keywords: therapeutic targets; colorectal cancer; cancer; angiogenesis ... See more keywords
Recent Development in Therapeutic Cardiac Patches
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2020.610364
Abstract: For the past decades, heart diseases remain the leading cause of death worldwide. In the adult mammalian heart, damaged cardiomyocytes will be replaced by non-contractile fibrotic scar tissues due to the poor regenerative ability of… read more here.
Keywords: recent development; development therapeutic; heart; cardiac patches ... See more keywords
Recent Advances and Future Perspectives in the Development of Therapeutic Approaches for Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Brain Sciences"
DOI: 10.3390/brainsci10090633
Abstract: Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and Huntington's disease (HD), severely impact the function of neuronal cells in the brain and have devastating consequences on the quality of life of patients… read more here.
Keywords: development therapeutic; future perspectives; perspectives development; neurodegenerative diseases ... See more keywords
Development, Therapeutic Evaluation and Theranostic Applications of Cubosomes on Cancers: An Updated Review
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030600
Abstract: Cancer is a group of disorders characterized by aberrant gene function and alterations in gene expression patterns. In 2020, it was anticipated that 19 million new cancer cases would be diagnosed globally, with around 10… read more here.
Keywords: theranostic applications; review; therapeutic evaluation; cancer ... See more keywords
A Comprehensive Review of the Development and Therapeutic Use of Antivirals in Flavivirus Infection
Sign Up to like & getrecommendations! Published in 2025 at "Viruses"
DOI: 10.3390/v17010074
Abstract: Flaviviruses are a diverse group of viruses primarily transmitted through hematophagous insects like mosquitoes and ticks. Significant expansion in the geographic range, prevalence, and vectors of flavivirus over the last 50 years has led to… read more here.
Keywords: review development; comprehensive review; antivirals flavivirus; development therapeutic ... See more keywords