Development of a UHPLC-MS method for inhibitor screening against α-L-1,3-fucosidase
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DOI: 10.1007/s00216-019-01575-x
Abstract: Abstractα-L-Fucosidase (AFU) is a promising therapeutic target for the treatment of inflammation, cancer, cystic fibrosis, and fucosidosis. Some of the existing analytical methods for the assessment of AFU activity are lacking in sensitivity and selectivity,… read more here.
Keywords: fucosidase; method; inhibitor screening; uhplc method ... See more keywords