3D printed controllable microporous scaffolds support embryonic development in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30810
Abstract: Little is known about the complex molecular and cellular events occurring during implantation, which represents a critical step for pregnancy. The conventional 2D culture could not support postimplantation embryos' normal development, and 3D conditions shed… read more here.
Keywords: embryonic development; development vitro; development; microporous scaffolds ... See more keywords
Development and in‐vitro characterization of a novel fetal vesicoamniotic shunt – The Vortex shunt
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6096
Abstract: To develop and test a novel vesicoamniotic shunt (VAS) to treat fetal lower urinary tract obstruction (LUTO), decrease dislodgement and optimize shunt deployment in‐vitro. read more here.
Keywords: characterization novel; vitro characterization; development vitro; vesicoamniotic shunt ... See more keywords
Development and in vitro evaluation of doxorubicin and celecoxib co-loaded bone targeted nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.02.004
Abstract: Abstract Bone metastasis is one of the major problems for the treatment of cancer. Doxorubicin (DOX) is a potential drug for the treatment of bone metastasis with a limited usage due to systemic side effects.… read more here.
Keywords: treatment; development vitro; bone; dox cxb ... See more keywords
Human brain development and its in vitro recapitulation
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Research"
DOI: 10.1016/j.neures.2018.09.011
Abstract: Humans have a large and gyrencephalic brain. The higher intellectual ability of humans is dependent on the proper development of the brain. Brain malformation is often associated with cognitive dysfunction. It is thus important to… read more here.
Keywords: development vitro; human brain; brain development; brain ... See more keywords
Development of an In Vitro Biomimetic Peripheral Neurovascular Platform
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c03861
Abstract: Nerves and blood vessels are present in most organs and are indispensable for their function and homeostasis. Within these organs, neurovascular (NV) tissue forms congruent patterns and establishes vital interactions. Several human pathologies, including diabetes… read more here.
Keywords: vitro; platform; development vitro; vitro biomimetic ... See more keywords
Formulation development, in vitro and in vivo evaluation of chitosan engineered nanoparticles for ocular delivery of insulin
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra07640f
Abstract: Insulin-dependent diabetic patients have to count on the administration of painful and discomforting insulin injections. However, inadequate insulin absorption and the risk of insulin level escalation in the blood are some disadvantages associated with insulin… read more here.
Keywords: insulin; vivo; insulin loaded; development vitro ... See more keywords
Development of in vitro three‐dimensional co‐culture system for metabolic syndrome therapeutic agents
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.1111/dom.13628
Abstract: There are many obstacles to overcome in the development of new drugs for metabolic diseases, including efficacy and toxicity problems in later stages of drug development. To overcome these problems and predict efficacy and toxicity… read more here.
Keywords: three dimensional; development vitro; dimensional culture; development ... See more keywords
Development of a 3D in vitro co-culture model of the airway mucosa using human primary cells
Sign Up to like & getrecommendations! Published in 2021 at "ERJ Open Research"
DOI: 10.1183/23120541.lsc-2021.30
Abstract: More than one billion people worldwide suffer from congenital and chronic respiratory diseases, leading to high rates in mortality and morbidity. The unpredictability of disease progression and responsiveness towards treatment requires sophisticated experimental models to… read more here.
Keywords: development vitro; primary cells; culture model; human primary ... See more keywords
Development of in vitro - in vivo correlations for newly optimized Nimesulide formulations
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0203123
Abstract: Use of the human volunteers in bioequivalence studies is being discouraged by the Food and drug administration after the introduction of biowaiver approaches. In-vitro in-vivo correlation (IVIVC) with the level A is accepted for the… read more here.
Keywords: vitro vivo; development vitro; drug; correlation ... See more keywords
Development and in vitro characterization of a humanized scFv against fungal infections
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276786
Abstract: The resistance and the birth of new intrinsic and multidrug-resistant pathogenic species like C. auris is creating great concern in the antifungal world. Given the limited drug arsenal and the lack of effectiveness of the… read more here.
Keywords: characterization humanized; vitro characterization; development vitro; scfv fungal ... See more keywords
Development and In Vitro Evaluation of Linear PEI-Shelled Heparin/Berberine Nanoparticles in Human Osteosarcoma U-2 OS Cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecules"
DOI: 10.3390/molecules23123121
Abstract: Berberine (BBR), a natural isoquinoline alkaloid derived from Chinese herbs, exerts many biological effects, including antiviral, antimicrobial, antidiarrhea, anti-inflammatory, and antitumor effects. In this study, a novel berberine nanoparticle (NP) consisting of heparin (HP) and… read more here.
Keywords: bbr bbr; bbr; development vitro; osteosarcoma cells ... See more keywords