Development and in vitro antiviral activity of ivermectin liposomes as a potential drug carrier system
Sign Up to like & getrecommendations! Published in 2024 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300708
Abstract: This study aimed to assess and compare diverse formulations of ivermectin‐loaded liposomes, employing lipid film hydration and ethanol injection methods. Three lipids (DOPC, SPC, and DSPC) were used in predetermined molar ratios. A total of… read more here.
Keywords: development vitro; ivermectin; drug; antiviral activity ... See more keywords
3D printed controllable microporous scaffolds support embryonic development in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30810
Abstract: Little is known about the complex molecular and cellular events occurring during implantation, which represents a critical step for pregnancy. The conventional 2D culture could not support postimplantation embryos' normal development, and 3D conditions shed… read more here.
Keywords: embryonic development; development vitro; development; microporous scaffolds ... See more keywords
Development and in‐vitro characterization of a novel fetal vesicoamniotic shunt – The Vortex shunt
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6096
Abstract: To develop and test a novel vesicoamniotic shunt (VAS) to treat fetal lower urinary tract obstruction (LUTO), decrease dislodgement and optimize shunt deployment in‐vitro. read more here.
Keywords: characterization novel; vitro characterization; development vitro; vesicoamniotic shunt ... See more keywords
Development of an in vitro method to assess the immunogenicity of biologics in the prevention of infectious diseases
Sign Up to like & getrecommendations! Published in 2025 at "Immunologic Research"
DOI: 10.1007/s12026-025-09681-y
Abstract: We present a series of preclinical studies focused on developing in vitro 2D and 3D models for assessing immunogenic factors in preventing infectious diseases. Human peripheral blood mononuclear cells (PBMC) and Calu-3 cell lines (bronchial… read more here.
Keywords: treated adv1; development vitro; infectious diseases; vitro method ... See more keywords
Development and in vitro evaluation of doxorubicin and celecoxib co-loaded bone targeted nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.02.004
Abstract: Abstract Bone metastasis is one of the major problems for the treatment of cancer. Doxorubicin (DOX) is a potential drug for the treatment of bone metastasis with a limited usage due to systemic side effects.… read more here.
Keywords: treatment; development vitro; bone; dox cxb ... See more keywords
Human brain development and its in vitro recapitulation
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Research"
DOI: 10.1016/j.neures.2018.09.011
Abstract: Humans have a large and gyrencephalic brain. The higher intellectual ability of humans is dependent on the proper development of the brain. Brain malformation is often associated with cognitive dysfunction. It is thus important to… read more here.
Keywords: development vitro; human brain; brain development; brain ... See more keywords
Development of an In Vitro Biomimetic Peripheral Neurovascular Platform
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c03861
Abstract: Nerves and blood vessels are present in most organs and are indispensable for their function and homeostasis. Within these organs, neurovascular (NV) tissue forms congruent patterns and establishes vital interactions. Several human pathologies, including diabetes… read more here.
Keywords: vitro; platform; development vitro; vitro biomimetic ... See more keywords
Formulation development, in vitro and in vivo evaluation of chitosan engineered nanoparticles for ocular delivery of insulin
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra07640f
Abstract: Insulin-dependent diabetic patients have to count on the administration of painful and discomforting insulin injections. However, inadequate insulin absorption and the risk of insulin level escalation in the blood are some disadvantages associated with insulin… read more here.
Keywords: insulin; vivo; insulin loaded; development vitro ... See more keywords
Development and in vitro evaluation of 1,4,7-triazacyclononane-coupled β-lactams against metallo-β-lactamase producing bacteria
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d5ra01842k
Abstract: Antimicrobial resistance (AMR) is a critical global issue, particularly against β-lactam antibiotics, which comprise over 60% of prescriptions. Metallo-β-lactamases (MBLs) are especially concerning as they inactivate nearly all β-lactams, except monobactams. Unlike serine-β-lactamases (SBLs), for… read more here.
Keywords: development vitro; mbl inhibitors; evaluation triazacyclononane; triazacyclononane coupled ... See more keywords
Development of in vitro three‐dimensional co‐culture system for metabolic syndrome therapeutic agents
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.1111/dom.13628
Abstract: There are many obstacles to overcome in the development of new drugs for metabolic diseases, including efficacy and toxicity problems in later stages of drug development. To overcome these problems and predict efficacy and toxicity… read more here.
Keywords: three dimensional; development vitro; dimensional culture; development ... See more keywords
Development of a 3D in vitro co-culture model of the airway mucosa using human primary cells
Sign Up to like & getrecommendations! Published in 2021 at "ERJ Open Research"
DOI: 10.1183/23120541.lsc-2021.30
Abstract: More than one billion people worldwide suffer from congenital and chronic respiratory diseases, leading to high rates in mortality and morbidity. The unpredictability of disease progression and responsiveness towards treatment requires sophisticated experimental models to… read more here.
Keywords: development vitro; primary cells; culture model; human primary ... See more keywords