Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase
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DOI: 10.1038/s41598-018-29150-x
Abstract: The xenotopic expression of the alternative oxidase AOX from the tunicate Ciona intestinalis in diverse models of human disease partially alleviates the phenotypic effects of mitochondrial respiratory chain defects. AOX is a non-proton pumping, mitochondrial… read more here.
Keywords: alternative oxidase; dna; developmental arrest; expression ... See more keywords