Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021006861
Abstract: Key Points • The fetal-to-adult transition in HSC states is associated with a global acquisition of megakaryocytic chromatin accessibility signatures.• The developmentally restricted expression of LIN28B suppresses establishment of an Mk-biased HSC pool early in… read more here.
Keywords: megakaryocyte priming; developmental cues; murine hematopoietic; cues license ... See more keywords
Developmental Cues and Molecular Drivers in Myelinogenesis: Revisiting Early Life to Re-Evaluate the Integrity of CNS Myelin
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DOI: 10.3390/cimb44070222
Abstract: The mammalian central nervous system (CNS) coordinates its communication through saltatory conduction, facilitated by myelin-forming oligodendrocytes (OLs). Despite the fact that neurogenesis from stem cell niches has caught the majority of attention in recent years,… read more here.
Keywords: myelinogenesis revisiting; developmental cues; drivers myelinogenesis; cues molecular ... See more keywords