Articles with "developmental functional" as a keyword



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Classical DC2 subsets and monocyte‐derived DC: Delineating the developmental and functional relationship

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Published in 2023 at "European Journal of Immunology"

DOI: 10.1002/eji.202149548

Abstract: To specifically tailor immune responses to a given pathogenic threat, dendritic cells (DC) are highly heterogeneous and comprise many specialized subtypes, including conventional DC (cDC) and monocyte‐derived DC (MoDC), each with distinct developmental and functional… read more here.

Keywords: developmental functional; functional relationship; immune responses; cdc2 ... See more keywords
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Developmental and Functional Heterogeneity of Monocytes.

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Published in 2018 at "Immunity"

DOI: 10.1016/j.immuni.2018.10.005

Abstract: Novel experimental approaches such as fate-mapping and single-cell analysis have brought fresh insight into monocyte development and function over the past decade and helped redefine the monocyte field. Monocytes are now known to consist of… read more here.

Keywords: heterogeneity; functional heterogeneity; heterogeneity monocytes; developmental functional ... See more keywords
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Unravelling the developmental and functional significance of an ancient Argonaute duplication

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-20003-8

Abstract: MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target regulation is considered crucial for animal physiology and development. However, this notion is based exclusively on studies in… read more here.

Keywords: functional significance; argonaute duplication; ancient argonaute; significance ancient ... See more keywords
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Developmental and functional heterogeneity of thermogenic adipose tissue

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Published in 2020 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjaa029

Abstract: Abstract The obesity epidemic continues to rise as a global health challenge. Thermogenic brown and beige adipocytes dissipate chemical energy as heat, providing an opportunity for developing new therapeutics for obesity and related metabolic diseases.… read more here.

Keywords: thermogenic adipose; functional heterogeneity; tissue; heterogeneity thermogenic ... See more keywords
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Developmental and Functional Control of Natural Killer Cells by Cytokines

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Published in 2017 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2017.00930

Abstract: Natural killer (NK) cells are effective in combating infections and tumors and as such are tempting for adoptive transfer therapy. However, they are not homogeneous but can be divided into three main subsets, including cytotoxic,… read more here.

Keywords: natural killer; functional control; developmental functional; control natural ... See more keywords
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Developmental and functional relationships between hypothalamic tanycytes and embryonic radial glia

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Published in 2023 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2022.1129414

Abstract: The hypothalamus is a key regulator of several homeostatic processes, such as circadian rhythms, energy balance, thirst, and thermoregulation. Recently, the hypothalamic third ventricle has emerged as a site of postnatal neurogenesis and gliogenesis. This… read more here.

Keywords: developmental functional; radial glia; embryonic radial; relationships hypothalamic ... See more keywords