Independent and cooperative roles of the Mek/ERK1/2‐MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23602
Abstract: Multiple extracellular and intracellular signals regulate the functions of oligodendrocytes as they progress through the complex process of developmental myelination and then maintain a functionally intact myelin sheath throughout adult life, preserving the integrity of… read more here.
Keywords: mek erk1; myelination; pi3k akt; developmental myelination ... See more keywords
Microglia phagocytose myelin sheaths to modify developmental myelination
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DOI: 10.1038/s41593-020-0654-2
Abstract: During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similarly to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown. Microglia, the resident immune cells of… read more here.
Keywords: neuronal activity; myelin sheaths; neurons synapses; developmental myelination ... See more keywords
Cc2d1b Contributes to the Regulation of Developmental Myelination in the Central Nervous System
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.881571
Abstract: Background Numerous studies have indicated that myelination is the result of the interplay between extracellular signals and an intricate network of transcription factors. Yet, the identification and characterization of the full repertoire of transcription factors… read more here.
Keywords: developmental myelination; cc2d1b; myelination; central nervous ... See more keywords
A Nutrient Formulation Affects Developmental Myelination in Term Infants: A Randomized Clinical Trial
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DOI: 10.3389/fnut.2022.823893
Abstract: Background and Objectives Observational studies suggest differences between breast-fed and formula-fed infants in developmental myelination, a key brain process for learning. The study aims to investigate the efficacy of a blend of docosahexaenoic acid (DHA),… read more here.
Keywords: myelination; clinical trial; developmental myelination; term infants ... See more keywords