Influence of developmental nicotine exposure on serotonergic control of breathing‐related motor output
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DOI: 10.1002/dneu.22866
Abstract: Serotonin plays an important role in the development of brainstem circuits that control breathing. Here, we test the hypothesis that developmental nicotine exposure (DNE) alters the breathing‐related motor response to serotonin (5HT). Pregnant rats were… read more here.
Keywords: breathing related; developmental nicotine; frequency; control breathing ... See more keywords
The interaction of the Chrna5 D398N variant with developmental nicotine exposure
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DOI: 10.1111/gbb.12474
Abstract: A single nucleotide polymorphism (SNP) in CHRNA5 (rs16969968, change from an aspartic acid [D] to asparagine [N] at position 398 of the human α5 nicotinic acetylcholine receptor subunit) has been associated with increased risk for… read more here.
Keywords: nicotine; nicotine exposure; nic offspring; interaction ... See more keywords
Developmental Nicotine Exposure Alters Synaptic Input to Hypoglossal Motoneurons and Is Associated with Altered Function of Upper Airway Muscles
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DOI: 10.1523/eneuro.0299-19.2019
Abstract: Abstract Nicotine exposure during the fetal and neonatal periods [developmental nicotine exposure (DNE)] is associated with ineffective upper airway protective reflexes in infants. This could be explained by desensitized chemoreceptors and/or mechanoreceptors, diminished neuromuscular transmission… read more here.
Keywords: nicotine exposure; upper airway; transmission; developmental nicotine ... See more keywords