Neuroscience Advances and the Developmental Origins of Health and Disease Research.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.9251
Abstract: Decades ago, when David Barker1 introduced the developmental origins of health and disease (DOHaD) conceptual model and later demonstrated that the prenatal period is relevant for future well-being, he could not have envisioned that fetal… read more here.
Keywords: stress; health; disease; development ... See more keywords
Timing the developmental origins of mammalian limb diversity
Sign Up to like & getrecommendations! Published in 2018 at "genesis"
DOI: 10.1002/dvg.23079
Abstract: Mammals have highly diverse limbs that have contributed to their occupation of almost every niche. Researchers have long been investigating the development of these diverse limbs, with the goals of identifying developmental processes and potential… read more here.
Keywords: limb; developmental origins; mammalian limb; limb diversity ... See more keywords
Translational insights on developmental origins of metabolic syndrome: Focus on fructose consumption
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Journal"
DOI: 10.1016/j.bj.2018.02.006
Abstract: Metabolic syndrome (MetS) is a highly prevalent complex trait despite recent advances in pathophysiology and pharmacological treatment. MetS can begin in early life by so-called the developmental origins of health and disease (DOHaD). The DOHaD… read more here.
Keywords: developmental origins; insights developmental; fructose consumption; translational insights ... See more keywords
Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.11.016
Abstract: Epigenetic alterations in the germline can be triggered by a number of different environmental factors from diet to toxicants. These environmentally induced germline changes can promote the epigenetic transgenerational inheritance of disease and phenotypic variation.… read more here.
Keywords: dmrs; developmental origins; inheritance; sperm ... See more keywords
Themed issue on cooperation between the Liggins Institute, New Zealand and the Japanese Developmental Origins of Health and Disease (DOHaD) society
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174418000375
Abstract: The Japan Society for Developmental Origins of Health and Disease (DOHaD-Japan) was launched in 2012 and became a Chapter member of Internal Society for DOHaD in 2014. The New Zealand–Japan Joint Seminar for DOHaD Epigenetics… read more here.
Keywords: new zealand; developmental origins; japan; health disease ... See more keywords
Developmental Origins of Health and Disease: Impact of environmental dust exposure in modulating microbiome and its association with non-communicable diseases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174420000549
Abstract: Abstract Non-communicable diseases (NCDs) including obesity, diabetes, and allergy are chronic, multi-factorial conditions that are affected by both genetic and environmental factors. Over the last decade, the microbiome has emerged as a possible contributor to… read more here.
Keywords: origins health; health; microbiome; health disease ... See more keywords
Translating developmental origins of health and disease in practice: health care providers’ perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174420001142
Abstract: 1Research Institute of the McGill University Health Center, Montreal, Quebec, Canada; 2Department of Psychiatry, McGill University, Montreal, Quebec, Canada; 3Hôpital Ste-Justine, Montreal, Quebec, Canada; 4Department of Psychiatry, Jewish General Hospital, Montreal, Quebec, Canada; 5Institut Universitaire… read more here.
Keywords: quebec canada; montreal quebec; health; developmental origins ... See more keywords
Developmental Origins of Health and Disease, resilience and social justice in the COVID era.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of developmental origins of health and disease"
DOI: 10.1017/s204017442100060x
Abstract: The COVID-19 pandemic has shone a spotlight on how health outcomes are unequally distributed among different population groups, with disadvantaged communities and individuals being disproportionality affected in terms of infection, morbidity and mortality, as well… read more here.
Keywords: origins health; health; health disease; social justice ... See more keywords
When a birth cohort grows up: challenges and opportunities in longitudinal developmental origins of health and disease (DOHaD) research
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174422000629
Abstract: Abstract High-quality evidence from prospective longitudinal studies in humans is essential to testing hypotheses related to the developmental origins of health and disease. In this paper, the authors draw upon their own experiences leading birth… read more here.
Keywords: health; origins health; developmental origins; birth ... See more keywords
Developmental origins and emerging therapeutic opportunities for childhood cancer
Sign Up to like & getrecommendations! Published in 2019 at "Nature Medicine"
DOI: 10.1038/s41591-019-0383-9
Abstract: Cancer is the leading disease-related cause of death in children in developed countries. Arising in the context of actively growing tissues, childhood cancers are fundamentally diseases of dysregulated development. Childhood cancers exhibit a lower overall… read more here.
Keywords: childhood; developmental origins; childhood cancers; therapeutic opportunities ... See more keywords
Developmental origins of health and disease: current knowledge and potential mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition Reviews"
DOI: 10.1093/nutrit/nux053
Abstract: Epidemiologic and clinical research has provided a large body of evidence supporting the developmental origins of health and disease (DOHaD), but there has been a relative dearth of mechanistic studies in humans due to the… read more here.
Keywords: developmental origins; potential mechanisms; health disease; health ... See more keywords