Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2016.11.011
Abstract: It is not understood why healthy tissues can exhibit varying levels of sensitivity to the same toxic stimuli. Using BH3 profiling, we find that mitochondria of many adult somatic tissues, including brain, heart, and kidneys,… read more here.
Keywords: mitochondrial apoptosis; regulation mitochondrial; sensitivity; cancer ... See more keywords
Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2023.1125071
Abstract: Acetylcholine and GABA are often co-released, including from VIP-expressing neurons of the cortex, cortically-projecting neurons of the globus pallidus externus and basal forebrain, and hippocampal-projecting neurons of the medial septum. The co-release of the functionally… read more here.
Keywords: cholinergic neurons; expression; regulation gabaergic; gaba ... See more keywords
Developmental Regulation of the Expression of Amaryllidaceae Alkaloid Biosynthetic Genes in Narcissus papyraceus
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10080594
Abstract: Amaryllidaceae alkaloids (AAs) have multiple biological effects, which are of interest to the pharmaceutical industry. To unleash the potential of Amaryllidaceae plants as pharmaceutical crops and as sources of AAs, a thorough understanding of the… read more here.
Keywords: narcissus papyraceus; expression amaryllidaceae; expression; biosynthetic genes ... See more keywords