A mutant O-GlcNAcase enriches Drosophila developmental regulators.
Sign Up to like & getrecommendations! Published in 2017 at "Nature chemical biology"
DOI: 10.1038/nchembio.2404
Abstract: Protein O-GlcNAcylation is a reversible post-translational modification of serines and threonines on nucleocytoplasmic proteins. It is cycled by the enzymes O-GlcNAc transferase (OGT) and O-GlcNAc hydrolase (O-GlcNAcase or OGA). Genetic approaches in model organisms have… read more here.
Keywords: drosophila developmental; enriches drosophila; glcnacase enriches; developmental regulators ... See more keywords
Developmental regulators moonlighting as transposons defense factors.
Sign Up to like & getrecommendations! Published in 2023 at "Andrology"
DOI: 10.1111/andr.13427
Abstract: BACKGROUND The germline perpetuates genetic information across generations. To maintain the integrity of the germline, transposable elements (TEs) in the genome must be silenced, as these mobile elements would otherwise engender widespread mutations passed on… read more here.
Keywords: regulators moonlighting; defense; transcriptional regulators; defense factors ... See more keywords
Application of developmental regulators to improve in planta or in vitro transformation in plants
Sign Up to like & getrecommendations! Published in 2022 at "Plant Biotechnology Journal"
DOI: 10.1111/pbi.13837
Abstract: Summary Plant genetic transformation is a crucial step for applying biotechnology such as genome editing to basic and applied plant science research. Its success primarily relies on the efficiency of gene delivery into plant cells… read more here.
Keywords: vitro transformation; developmental regulators; plant; transformation ... See more keywords