The development of cell senescence
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2019.110742
Abstract: Cellular senescence was traditionally considered a stress response that protected the organism by limiting the proliferation of damaged and unwanted cells. However, the recent identification of developmentally-programmed cellular senescence during embryo development has changed our… read more here.
Keywords: development cell; cell senescence; senescence; developmental senescence ... See more keywords
Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase
Sign Up to like & getrecommendations! Published in 2017 at "Autophagy"
DOI: 10.1080/15548627.2016.1256934
Abstract: ABSTRACT Spns1 (Spinster homolog 1 [Drosophila]) in vertebrates, as well as Spin (Spinster) in Drosophila, is a hypothetical lysosomal H+-carbohydrate transporter, which functions at a late stage of macroautophagy (hereafter autophagy). The Spin/Spns1 defect induces… read more here.
Keywords: spns1 atpase; atpase; senescence; developmental senescence ... See more keywords