Developmental Timing of Adversity and Mental Health Across the Lifespan-Time to Rethink Sensitive Periods?
Sign Up to like & getrecommendations! Published in 2024 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2024.29376
Abstract: Associations of adversity in the form of traumatic experiences and stressful events with health outcomes are well appreciated, particularly when adversity is experienced early in the lifespan. 1 Copeland and colleagues 2 address an open… read more here.
Keywords: mental health; stressful events; developmental timing; adversity ... See more keywords
A Neuropeptide Signaling Network That Regulates Developmental Timing and Systemic Growth in Drosophila
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25677
Abstract: Animals sense chemical cues such as nutritious and noxious stimuli through the chemosensory system and adapt their behavior, physiology, and developmental schedule to the environment. In the Drosophila central nervous system, chemosensory interneurons that produce… read more here.
Keywords: systemic growth; hug neurons; developmental timing; hug ... See more keywords
Developmental Timing of Trauma in Women Predicts Unique Extracellular Vesicle Proteome Signatures
Sign Up to like & getrecommendations! Published in 2021 at "Biological psychiatry"
DOI: 10.1016/j.biopsych.2021.08.003
Abstract: BACKGROUND Exposure to traumatic events is a risk factor for negative physical and mental health outcomes. However, the underlying biological mechanisms that perpetuate these lasting effects are not known. METHODS We investigated the impact and… read more here.
Keywords: specific developmental; sexual trauma; health outcomes; timing trauma ... See more keywords
Distribution and developmental timing of zebrafish liver innervation
Sign Up to like & getrecommendations! Published in 2024 at "Biology Letters"
DOI: 10.1098/rsbl.2024.0288
Abstract: Hepatic innervation regulates multiple aspects of liver function, repair and regeneration, and liver denervation is associated with higher rates of metabolic disorders in humans. However, the mechanisms regulating the development of the hepatic nervous system,… read more here.
Keywords: hepatic innervation; hepatic nervous; developmental timing; innervation ... See more keywords
Developmental timing of programmed DNA elimination in Paramecium tetraurelia recapitulates germline transposon evolutionary dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Genome Research"
DOI: 10.1101/2022.05.18.492358
Abstract: With its nuclear dualism, the ciliate Paramecium constitutes an original model to study how host genomes cope with transposable elements (TEs). P. tetraurelia harbors two germline micronuclei (MIC) and a polyploid somatic macronucleus (MAC) that… read more here.
Keywords: paramecium; dna elimination; developmental timing; elimination ... See more keywords
Developmental Timing is Everything (Part II): Gating of High Temperature Responses by the Circadian Clock[OPEN]
Sign Up to like & getrecommendations! Published in 2019 at "Plant Cell"
DOI: 10.1105/tpc.19.00632
Abstract: Arabidopsis ( Arabidopsis thaliana ) seedlings exposed to heat stress (>42°C) suffer high lethality rates unless exposed to milder heat (37°C) beforehand. This pre-exposure distinguishes basal from acquired thermotolerance and has been extensively studied over… read more here.
Keywords: timing everything; high temperature; part gating; everything part ... See more keywords
The BMP2/4 ortholog Dpp can function as an inter-organ signal that regulates developmental timing
Sign Up to like & getrecommendations! Published in 2018 at "Life Science Alliance"
DOI: 10.26508/lsa.201800216
Abstract: Increased local trapping of morphogens within tissues as they grow would reduce circulating levels and can therefore provide a systemic readout of the status of their growth and maturation. Developmental transitions are often triggered by… read more here.
Keywords: ortholog dpp; bmp2 ortholog; growth; dpp function ... See more keywords