Articles with "developmental toxicity" as a keyword



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Developmental toxicity induced by triclosan exposure in zebrafish embryos

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Published in 2022 at "Birth Defects Research"

DOI: 10.1002/bdr2.1982

Abstract: The present study aimed to investigate the acute toxicity and the developmental alterations induced by triclosan (TCS) exposure in zebrafish early‐life stages using fish embryo acute toxicity tests as a methodological approach. read more here.

Keywords: developmental toxicity; induced triclosan; exposure zebrafish; toxicity ... See more keywords
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Identifying the landscape of developmental toxicity new approach methodologies

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Published in 2022 at "Birth Defects Research"

DOI: 10.1002/bdr2.2075

Abstract: The dynamics and complexities of in utero fetal development create significant challenges in transitioning from lab animal‐centric developmental toxicity testing methods to assessment strategies based on new approach methodologies (NAMs). Nevertheless, considerable progress is being… read more here.

Keywords: developmental toxicity; new approach; landscape developmental; toxicity ... See more keywords
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Embryo‐fetal developmental toxicity and toxicokinetics of loxoprofen tromethamine intravenously administered to pregnant rats

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Published in 2022 at "Birth Defects Research"

DOI: 10.1002/bdr2.2116

Abstract: Loxoprofen tromethamine is a novel structural compound related to loxoprofen. It has been used for the treatment of pain and inflammation. However, the embryo‐fetal developmental toxicity (EFDT) of loxoprofen tromethamine has not been evaluated in… read more here.

Keywords: developmental toxicity; fetal developmental; embryo fetal; toxicokinetics loxoprofen ... See more keywords
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Developmental toxicity induced by brodifacoum in zebrafish (Danio rerio) early life stages

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Published in 2022 at "Birth Defects Research"

DOI: 10.1002/bdr2.2118

Abstract: The present study mainly focused on the assessment of developmental toxicity induced by exposure to brodifacoum (BDF) in zebrafish at early life stages. read more here.

Keywords: developmental toxicity; early life; life stages; toxicity induced ... See more keywords
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The role of receptor‐mediated activities of 4‐ and 5‐ring unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs) in developmental toxicity

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Published in 2022 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4428

Abstract: The present study evaluated the aryl hydrocarbon receptor (AhR), estrogen receptor‐α (ER‐α), and retinoic acid receptor (RAR) mediated activities of nine 4‐ and 5‐ring unsubstituted and monomethylated polycyclic aromatic hydrocarbons (PAHs) using a series of… read more here.

Keywords: developmental toxicity; pahs; ring unsubstituted; receptor ... See more keywords
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Developmental toxicity of triclocarban in zebrafish (Danio rerio) embryos

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Published in 2019 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22289

Abstract: Triclocarban (TCC), which is used as an antimicrobial agent in personal care products, has been widely detected in aquatic ecosystems. However, the consequence of TCC exposure on embryo development is still elusive. Here, by using… read more here.

Keywords: toxicity triclocarban; exposure; triclocarban zebrafish; tcc exposure ... See more keywords
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Environmental relevant concentrations of triclosan affected developmental toxicity, oxidative stress, and apoptosis in zebrafish embryos

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Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23448

Abstract: Triclosan (TCS), as a broad‐spectrum antibacterial agent, is widely used in various pharmaceutical and personal care products. However, the details of ecological environmental health risks of TCS are not clear. In this study, zebrafish embryos/larval… read more here.

Keywords: developmental toxicity; apoptosis; tcs; 250 tcs ... See more keywords
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Morphology-Based Whole Embryo Culture for Developmental Toxicity of Drugs.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7883-0_8

Abstract: In vivo pregnant study protocols covering preconceptional exposure as well as prenatal and postnatal development including the lactation period to screen the toxic effects on specific elements of the highly complicated reproductive cycle are time-consuming… read more here.

Keywords: embryo culture; based whole; developmental toxicity; whole embryo ... See more keywords
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Developmental toxicity and angiogenic defects of etoxazole exposed zebrafish (Danio rerio) larvae.

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Published in 2019 at "Aquatic toxicology"

DOI: 10.1016/j.aquatox.2019.105324

Abstract: Etoxazole, a chitin synthesis inhibitor, is widely used to control insects and mites by causing developmental defects. Despite the many advantages of pesticides, the inhibitory effects of most pesticides including etoxazole are based on biochemical… read more here.

Keywords: aquatic organisms; angiogenic defects; toxicity angiogenic; effects etoxazole ... See more keywords
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Developmental toxicity induced by particulate matter (PM2.5) in zebrafish (Danio rerio) model.

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Published in 2021 at "Aquatic toxicology"

DOI: 10.1016/j.aquatox.2021.105928

Abstract: Contemporary research in epidemiology has found that being exposed to air pollution at an early stage of life has associations with both acute and chronic conditions of the multi-organs. Nevertheless, the reasons for this have… read more here.

Keywords: pm2; toxicity; matter pm2; zebrafish danio ... See more keywords
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Prenatal developmental toxicity evaluation of Verbena officinalis during gestation period in female Sprague-Dawley rats.

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Published in 2019 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2019.02.016

Abstract: Verbena officinalis is widely used by women for maintaining general health and treating various gynaecological disorders during pregnancy. A case report has indicated that the consumption of V. officinalis induced an abortifacient effect. Hence, this… read more here.

Keywords: gestation; verbena officinalis; toxicity; prenatal developmental ... See more keywords