Homology modeling of human GABA-AT and devise some novel and potent inhibitors via computer-aided drug design techniques
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DOI: 10.1080/07391102.2020.1774417
Abstract: Abstract γ-aminobutyric acid aminotransferase (GABA-AT) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme which degrades γ-aminobutyric (GABA) in the brain. GABA is an important inhibitory neurotransmitter that plays important neurological roles in the brain. Therefore, GABA-AT is… read more here.
Keywords: novel potent; drug; devise novel; gaba ... See more keywords