Incidence and Visual Outcomes of Culture-Proven Endophthalmitis Following Dexamethasone Intravitreal Implant
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2016.5883
Abstract: Importance The rate of endophthalmitis following dexamethasone intravitreal implant (DEX) has varied in large clinical trials. Furthermore, to our knowledge, the optimal management of eyes with endophthalmitis associated with DEX has not been established. Objective… read more here.
Keywords: endophthalmitis following; dex; endophthalmitis; culture proven ... See more keywords
Sustained Release of Dexamethasone from Sulfobutyl Ether β-cyclodextrin Modified Self-Assembling Peptide Nanoscaffolds in a Perinatal Rat Model of Hypoxia-Ischemia.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900083
Abstract: Inflammation plays a critical role in the development of hypoxia-ischemia (HI) induced newborn brain damage. A localized, sustained delivery of dexamethasone (Dex) through an intracerebral injection could reduce the inflammatory response in the injured perinatal… read more here.
Keywords: hypoxia ischemia; dex; sbe rada; sulfobutyl ether ... See more keywords
Biomimetic Metal−Organic Frameworks as Targeted Vehicles to Enhance Osteogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102821
Abstract: Although engineered nanoparticles loaded with specific growth factors are used to regulate differentiation of stem cells, the low loading efficiency and biocompatibility are still great challenges in tissue repair. A nature‐inspired biomimetic delivery system with… read more here.
Keywords: zif scm; dex zif; osteogenesis; scm ... See more keywords
Cationic Polysaccharide Conjugates as Antibiotic Adjuvants Resensitize Multidrug‐Resistant Bacteria and Prevent Resistance
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204065
Abstract: In recent years, traditional antibiotic efficacy has rapidly diminished due to the advent of multidrug‐resistant (MDR) bacteria, which poses severe threat to human life and globalized healthcare. Currently, the development cycle of new antibiotics cannot… read more here.
Keywords: polysaccharide conjugates; dex; dex pss30; cationic polysaccharide ... See more keywords
DEX-Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T-Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202205854
Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant blood disorder with a high rate of relapse. Patients relapse as a result of minimal residual disease (MRD), which originates from residual T-ALL cells in the… read more here.
Keywords: cell; leukemia; dex; acute lymphoblastic ... See more keywords
Nrf2 mediates the antinociceptive activity of dexmedetomidine in an acute inflammatory visceral pain rat model by activating the NF‐κB sensor
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3456
Abstract: Dexmedetomidine (DEX) is a highly selective α2 adrenoceptor agonist. In this study, we evaluated the antalgic effect of DEX on acetic acid–induced acute inflammatory visceral pain (AIVP) in rats. Additionally, we evaluated the role of… read more here.
Keywords: acute inflammatory; dex; nrf2; model ... See more keywords
Dexmedetomidine attenuates hypoxia‐induced cardiomyocyte injury by promoting telomere/telomerase activity: Possible involvement of ERK1/2‐Nrf2 signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11799
Abstract: Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, possesses cardioprotection against ischemic/hypoxic injury, but the exact mechanism is not fully elucidated. Since telomere/telomerase dysfunction is involved in myocardial ischemic damage, the present study aimed to investigate… read more here.
Keywords: signaling pathway; nrf2 signaling; dex; erk1 nrf2 ... See more keywords
Alpha‐glucosidase enzyme immobilized Dextran‐Co metal nanoparticle cryogel composite systems as dual catalyst with enhanced stability and catalytic activity
Sign Up to like & getrecommendations! Published in 2023 at "ChemCatChem"
DOI: 10.1002/cctc.202201498
Abstract: Here, dextran (Dex) cryogels were prepared and used for the immobilization of α‐Glu enzyme via two different techniques of entrapment and covalent linking. The entrapment of α‐Glu enzyme within Dex cryogels (α‐GluE@Dex) during the synthesis… read more here.
Keywords: dex cryogels; cryogel; dex; activity ... See more keywords
Protective and therapeutic effects of dexpanthenol on isoproterenol‐induced cardiac damage in rats
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DOI: 10.1002/jcb.27058
Abstract: The purpose of the study was to explore the protective and therapeutic effects of dexpanthenol (DEX) on isoproterenol (ISO)‐induced cardiac damage. Forty rats were distributed into four groups: group I (Control); group II (ISO); ISO… read more here.
Keywords: iso; dex; effects dexpanthenol; group ... See more keywords
Dexmedetomidine alleviates lipopolysaccharide‐induced acute kidney injury by inhibiting the NLRP3 inflammasome activation via regulating the TLR4/NOX4/NF‐κB pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29173
Abstract: Dexmedetomidine (DEX) prevents kidney damage caused by sepsis, but the mechanism of this effect remains unclear. In this study, the protective molecular mechanism of DEX in lipopolysaccharide (LPS)‐induced acute kidney injury was investigated and its… read more here.
Keywords: inflammasome activation; dex; damage; nlrp3 inflammasome ... See more keywords
Dexmedetomidine protects cardiomyocytes against hypoxia/reoxygenation injury via multiple mechanisms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.24119
Abstract: BACKGROUND Myocardial infarction (MI) is a serious cardiovascular disease associated with myocardial ischemia/reperfusion (I/R) injury. Dexmedetomidine (Dex), an α2-adrenoceptor agonist, has been reported to protect against I/R injury. We examined the cardioprotective effects of Dex… read more here.
Keywords: hypoxia reoxygenation; injury; measured using; dex ... See more keywords