Hyperoside exerts osteoprotective effect on dexamethasone-induced osteoblasts by targeting NADPH Oxidase 4 (NOX4) to inhibit the reactive oxygen species (ROS) accumulation and activate c-Jun N-terminal kinase (JNK) pathway
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DOI: 10.1080/21655979.2022.2054499
Abstract: ABSTRACT Hyperoside (Hyp) is a flavonoid active compound deriving from Chinese herbal medicines. Increasing studies have implicated that Hyp may serve as a predominant promoting factor in osteoblast differentiation. This paper investigates whether Hyp could… read more here.
Keywords: hyp; induced cells; dex; jnk pathway ... See more keywords
Blockade of cyclophilin D rescues dexamethasone-induced oxidative stress in gingival tissue
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DOI: 10.1371/journal.pone.0173270
Abstract: Glucocorticoids (GCs) are frequently used for the suppression of inflammation in chronic inflammatory diseases. Excessive GCs usage is greatly associated with several side effects, including gingival ulceration, the downward migration of the epithelium, attachment loss… read more here.
Keywords: dex; gingival tissue; induced oxidative; dex induced ... See more keywords
Laurel Attenuates Dexamethasone-Induced Skeletal Muscle Atrophy In Vitro and in a Rat Model
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DOI: 10.3390/nu14102029
Abstract: Prevention of muscle atrophy contributes to improved quality of life and life expectancy. In this study, we investigated the effects of laurel, selected from 34 spices and herbs, on dexamethasone (DEX)-induced skeletal muscle atrophy and… read more here.
Keywords: induced skeletal; muscle; muscle atrophy; dex induced ... See more keywords