An E-selectin targeting and MMP-2-responsive dextran-curcumin polymeric prodrug for targeted therapy of acute kidney injury.
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DOI: 10.1039/c8bm00813b
Abstract: Based on the overproduction of matrix metalloproteinase-2 (MMP-2) in renal tissue during acute kidney injury (AKI) occurrence, we developed a MMP-2 enzyme-triggered polymeric prodrug with sialic acid (SA) as the targeting group to the inflamed… read more here.
Keywords: dex; pvglig cur; polymeric prodrug; pvglig ... See more keywords