Dexamethasone acetate nanocrystals: characterization and dissolution studies in presence of polymorphic phases.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical nanotechnology"
DOI: 10.2174/2211738511666230328134440
Abstract: BACKGROUND A drug with poor water-solubility, like Dexamethasone acetate, can present lower bioavailability conventional for pharmaceutical formulations, and the presence of polymorphs in the raw material can lead to drug quality problems. OBJECTIVE In this… read more here.
Keywords: dissolution studies; dexamethasone; dexamethasone acetate; presence ... See more keywords
Investigation of Combined Cyclodextrin and Hydrogel Formulation for Ocular Delivery of Dexamethasone Acetate by Means of Experimental Designs
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DOI: 10.3390/pharmaceutics10040249
Abstract: Dexamethasone acetate (DXMa) has proven its efficiency to treat corneal inflammation, without a great propensity to increase intraocular pressure. Unfortunately, its poor aqueous solubility, associated with a rapid precorneal elimination, results in a low drug… read more here.
Keywords: dxma; dexamethasone acetate; ocular delivery;
Nanostructured Lipid Carriers for Enhanced Transscleral Delivery of Dexamethasone Acetate: Development, Ex Vivo Characterization and Multiphoton Microscopy Studies
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DOI: 10.3390/pharmaceutics15020407
Abstract: Corticosteroids, although highly effective for the treatment of both anterior and posterior ocular segment inflammation, still nowadays struggle for effective drug delivery due to their poor solubilization capabilities in water. This research work aims to… read more here.
Keywords: nanostructured lipid; lipid carriers; microscopy; dexamethasone acetate ... See more keywords