Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
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DOI: 10.1111/jmp.12602
Abstract: We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol… read more here.
Keywords: dose cortisol; dexamethasone dose; common marmosets; suppression ... See more keywords
Rationale of a lower dexamethasone dose in prenatal congenital adrenal hyperplasia therapy based on pharmacokinetic modelling.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-21-0395
Abstract: CONTEXT Prenatal dexamethasone therapy is used in female foetuses with congenital adrenal hyperplasia to suppress androgen excess and prevent virilisation of the external genitalia. The traditional dexamethasone dose of 20 µg/kg/d has been used since decades… read more here.
Keywords: therapy; dexamethasone dose; adrenal hyperplasia; dexamethasone ... See more keywords