Suppressive effects of processed aconite root on dexamethasone-induced muscle ring finger protein-1 expression and its active ingredients.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural medicines"
DOI: 10.1007/s11418-022-01606-5
Abstract: Processed aconite root (PA), the tuberous root of Aconitum carmichaelii prepared by autoclaving, is a crude drug used in Japanese traditional Kampo medicine and traditional Chinese medicine for the symptoms of kidney deficiency, that is… read more here.
Keywords: active ingredients; expression; muscle; dexamethasone induced ... See more keywords
Leonurine protects against dexamethasone-induced cytotoxicity in pancreatic β-cells via PI3K/Akt signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.184
Abstract: Glucocorticoid excess induces pancreatic β-cell apoptosis and insulin secretion impairment, which may lead to hyperglycemia and steroid diabetes. Leonurine is a natural alkaloid extracted from the Herba leonuri, which has been widely used in the… read more here.
Keywords: dexamethasone induced; pancreatic cells; induced cytotoxicity; dexamethasone ... See more keywords
DEXAMETHASONE-INDUCED HICCUPS IN A PATIENT WITH COVID-19 PNEUMONIA
Sign Up to like & getrecommendations! Published in 2021 at "Chest"
DOI: 10.1016/j.chest.2021.07.478
Abstract: TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: Dexamethasone has been shown to reduce 28-day mortality in patients with severe COVID-19 pneumonia who required oxygen supplementation or invasive mechanical ventilation according to the RECOVERY… read more here.
Keywords: dexamethasone; dexamethasone induced; induced hiccups; covid pneumonia ... See more keywords
The expression profiling and ontology analysis of non-coding RNAs in dexamethasone induced steatosis in hepatoma cell.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.01.089
Abstract: Increasing amounts of evidence have indicated that non-coding RNAs (ncRNAs) have important regulatory potential in various biological processes. However, the contribution of ncRNAs, especially long non-coding RNAs (lncRNAs) to drug induced steatosis remain largely unknown.… read more here.
Keywords: dexamethasone induced; ontology; expression; cell ... See more keywords
Mitigation of dexamethasone-induced nephrotoxicity by modulating the activity of adrenergic receptors: Implication of Wnt/β-arrestin2/β-catenin pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120304
Abstract: The present study aimed to investigate the role of α and β-adrenergic receptors (βARs) in mediation or modulation of the dexamethasone-induced nephrotoxicity by using different pharmacological interventions. Nephrotoxicity was induced by subcutaneous injection of dexamethasone… read more here.
Keywords: catenin; dexamethasone induced; arrestin2; induced nephrotoxicity ... See more keywords
Trimetazidine attenuates dexamethasone-induced muscle atrophy via inhibiting NLRP3/GSDMD pathway-mediated pyroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00648-0
Abstract: Skeletal muscle atrophy is one of the major side effects of high dose or sustained usage of glucocorticoids. Pyroptosis is a novel form of pro-inflammatory programmed cell death that may contribute to skeletal muscle injury.… read more here.
Keywords: dexamethasone induced; pyroptosis; muscle; trimetazidine ... See more keywords
Trigonelline Demonstrated Ameliorative Effects in Dexamethasone Induced Osteoporotic Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Drug research"
DOI: 10.1055/a-1147-5724
Abstract: AIM Trigonelline is a potent phytochemical present in fenugreek, which has strong anti-oxidant and phytoestrogenic activities. This study was carried out to investigate this estrogenic activity as a possible mechanisms involved in preventing the symptoms… read more here.
Keywords: dexamethasone induced; ameliorative effects; demonstrated ameliorative; trigonelline demonstrated ... See more keywords
A Lignan from Alnus japonica Activates Myogenesis and Alleviates Dexamethasone-induced Myotube Atrophy
Sign Up to like & getrecommendations! Published in 2022 at "Planta Medica"
DOI: 10.1055/a-1891-3366
Abstract: Abstract To find inhibitors against skeletal muscle loss, we isolated a lignan compound ((−)-(2 R ,3 R -1,4-O-diferuloylsecoisolarciresinol, DFS) from the stem of Alnus japonica . C2C12 myoblasts were treated with DFS during differentiation. To… read more here.
Keywords: dfs; alnus japonica; japonica; dexamethasone induced ... See more keywords
Phlomis umbrosa Turcz. Water Extract Attenuates Dexamethasone-Induced Muscle Atrophy by Regulating PI3K/Akt/mTOR Pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal food"
DOI: 10.1089/jmf.2025.k.0050
Abstract: Skeletal muscles, attached to bones via tendons, enable physical movement in animals. Muscle atrophy is associated with a decline in muscle mass and function and can detrimentally impact quality of life, leading to muscle weakness,… read more here.
Keywords: muscle; muscle atrophy; umbrosa turcz; dexamethasone induced ... See more keywords
7-Hydroxyflavone Mitigates Osteoporosis Via Key Signaling Pathways in a Dexamethasone-induced Rat Model.
Sign Up to like & getrecommendations! Published in 2025 at "Current topics in medicinal chemistry"
DOI: 10.2174/0115680266387622250519052501
Abstract: BACKGROUND Osteoporosis is a deteriorating skeletal bone disorder that affects in a silent, asymptomatic way. On-demand for new therapeutic strategies, natural products have gained attention as a significant alternative for treating osteoporosis. 7-Hydroxyflavone (7HF) is… read more here.
Keywords: hydroxyflavone; analysis; osteoporosis; bone ... See more keywords
Dexamethasone-associated regression of glioblastoma
Sign Up to like & getrecommendations! Published in 2025 at "Surgical Neurology International"
DOI: 10.25259/sni_818_2024
Abstract: Background: Dexamethasone-induced regression of an intracranial space-occupying lesion is commonly characteristic of primary central nervous system lymphoma (PCNSL). However, dexamethasone does not have an established chemotherapeutic role in glioblastoma multiforme (GBM). This is a report… read more here.
Keywords: glioblastoma; regression; case; dexamethasone ... See more keywords