Substrate Determinants for Unwinding Activity of the DExH/D-Box Protein RNA Helicase A.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b01025
Abstract: RNA helicase A (RHA) as a member of the DExH/D-box subgroup of helicase superfamily II is involved in virtually all aspects of RNA metabolism. It exhibits robust RNA helicase activity in vitro. However, little is… read more here.
Keywords: substrate determinants; rna helicase; dexh box; rha ... See more keywords
Molecular Basis of RNA-Driven ATP Hydrolysis in DExH-Box Helicases.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c11980
Abstract: The spliceosome machinery catalyzes precursor messenger (pre-m)RNA splicing. In each cycle, the spliceosome experiences massive compositional and conformational remodeling fueled by the concerted action of specific RNA-dependent ATPases/helicases. Intriguingly, these enzymes are allosterically activated to… read more here.
Keywords: dexh box; rna; atp hydrolysis;
Nucleoplasmic Nup98 controls gene expression by regulating a DExH/D-box protein
Sign Up to like & getrecommendations! Published in 2018 at "Nucleus"
DOI: 10.1080/19491034.2017.1364826
Abstract: ABSTRACT The nucleoporin Nup98 has been linked to the regulation of transcription and RNA metabolism,1-3 but the mechanisms by which Nup98 contributes to these processes remains largely undefined. Recently, we uncovered interactions between Nup98 and… read more here.
Keywords: nucleoplasmic nup98; gene expression; nup98; gene ... See more keywords