Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2021.28886
Abstract: Importance Postoperative ileus is common after abdominal surgery, and small clinical studies have reported that intraoperative administration of dexmedetomidine may be associated with improvements in postoperative gastrointestinal function. However, findings have been inconsistent and study… read more here.
Keywords: dexmedetomidine; abdominal surgery; gastrointestinal function; time first ... See more keywords
Effect of Perioperative Dexmedetomidine on Delayed Graft Function Following a Donation-After-Cardiac-Death Kidney Transplant
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.15217
Abstract: This randomized clinical trial compares outcomes among patients who received a donated-after-cardiac-death kidney allograft and either dexmedetomidine or placebo during and after the surgical procedure. read more here.
Keywords: death kidney; effect perioperative; dexmedetomidine; cardiac death ... See more keywords
Comment on ‘Intrathecal dexmedetomidine and postoperative pain: A systematic review and meta‐analysis of randomized controlled trials’
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Pain"
DOI: 10.1002/ejp.1852
Abstract: We had the great pleasure of reading the article titled "Intrathecal dexmedetomidine and postoperative pain: A systematic review and meta-analysis of randomized controlled trials" written by Paramasivan et al. The authors concluded that "the analgesic… read more here.
Keywords: dexmedetomidine postoperative; postoperative pain; dexmedetomidine; pain systematic ... See more keywords
Blind method regarding the effect of dexmedetomidine on CRBD
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2497-5
Abstract: We have read an article written by Kwon et al. with great interest [1]. It is a welcome investigation which evaluated the effect of the intraoperative dexmedetomidine (DEX) on the incidence and severity of catheter-related… read more here.
Keywords: blind method; dex; group; effect ... See more keywords
Comparison of single minimum dose administration of dexmedetomidine and midazolam for prevention of emergence delirium in children: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Anesthesia"
DOI: 10.1007/s00540-019-02705-6
Abstract: Purpose Emergence delirium (ED) is common in children after sevoflurane anesthesia and should be prevented for patient safety. A prospective, double-blind, randomized, controlled study was performed to compare the efficacy of minimal dosage of midazolam… read more here.
Keywords: dexmedetomidine; emergence delirium; group; midazolam ... See more keywords
CD200R Is Involved in the Anti-inflammatory Effect of Dexmedetomidine in Lipopolysaccharide-Stimulated Microglia
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01244-7
Abstract: Dexmedetomidine has been confirmed to have anti-inflammatory effect in numerous diseases. However, the detailed mechanism is still unknown. We explore the hypothesis that CD200R is related to the anti-inflammatory effect of dexmedetomidine. Primary microglia were… read more here.
Keywords: anti inflammatory; effect dexmedetomidine; inflammatory effect; effect ... See more keywords
Effects of topical application of tramadol with/without dexmedetomidine and proparacaine on corneal sensitivity in rats
Sign Up to like & getrecommendations! Published in 2020 at "International Ophthalmology"
DOI: 10.1007/s10792-020-01596-x
Abstract: To evaluate the corneal anesthetic effect following topical application of tramadol alone and in combination with dexmedetomidine, and compare it to proparacaine, in clinically healthy rats. A randomized, crossover study was performed. Twenty Wistar albino… read more here.
Keywords: topical application; corneal; tramadol; dexmedetomidine ... See more keywords
Dexmedetomidine reduces neuropathic pain in a rat model of skin/muscle incision and retraction.
Sign Up to like & getrecommendations! Published in 2017 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2015.10.009
Abstract: BACKGROUND Dexmedetomidine has been proposed as a novel anesthetic adjuvant. However, it remains unclear whether peripheral administration of dexmedetomidine is safe and effective to reduce acute postoperative pain. This study aimed to examine the effects… read more here.
Keywords: skin muscle; incision retraction; muscle incision; group ... See more keywords
Dexmedetomidine attenuates sepsis-associated inflammation and encephalopathy via central α2A adrenoceptor
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.10.008
Abstract: Sepsis-associated encephalopathy (SAE) is a significant clinical issue that is associated with increased mortality and cost of health care. Dexmedetomidine, an α2 adrenoceptor agonist that is used to provide sedation, has been shown to induce… read more here.
Keywords: clp; inflammation; sepsis associated; dexmedetomidine ... See more keywords
[A prospective, randomized, double-blinded control study on comparison of tramadol, clonidine and dexmedetomidine for post spinal anesthesia shivering].
Sign Up to like & getrecommendations! Published in 2018 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2017.04.019
Abstract: INTRODUCTION Shivering, a common intraoperative problem under spinal anesthesia increases the oxygen consumption considerably and is uncomfortable and distressing to the patient, anesthesiologist as well as surgeon. The present study was designed to explore the… read more here.
Keywords: tramadol; control; group; spinal anesthesia ... See more keywords
[Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats].
Sign Up to like & getrecommendations! Published in 2019 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2018.09.011
Abstract: BACKGROUND AND OBJECTIVES Dexmedetomidine has demonstrated protective effects against lung injury in vitro. Here, we investigated whether dexmedetomidine preconditioning protected against lung injury in hemorrhagic shock rats. METHODS Male Sprague-Dawley rats were randomly divided into… read more here.
Keywords: dexmedetomidine; dexmedetomidine preconditioning; lung injury; hemorrhagic shock ... See more keywords