[Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats].
Sign Up to like & getrecommendations! Published in 2019 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2018.09.011
Abstract: BACKGROUND AND OBJECTIVES Dexmedetomidine has demonstrated protective effects against lung injury in vitro. Here, we investigated whether dexmedetomidine preconditioning protected against lung injury in hemorrhagic shock rats. METHODS Male Sprague-Dawley rats were randomly divided into… read more here.
Keywords: dexmedetomidine; dexmedetomidine preconditioning; lung injury; hemorrhagic shock ... See more keywords
Dexmedetomidine preconditioning alleviated murine liver ischemia and reperfusion injury by promoting macrophage M2 activation via PPARĪ³/STAT3 signaling.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106363
Abstract: BACKGROUND Although a protective role of dexmedetomidine in liver ischemia and reperfusion (IR) injury has been reported, the underlying mechanism remains to be determined. The aim of this study is to analyze the effects of… read more here.
Keywords: macrophage activation; activation; dexmedetomidine; injury ... See more keywords